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Whole-Genome Analysis of Cryptococcus gattii, Southeastern United States
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  1. Timing the Origin of Cryptococcus gattii sensu stricto, Southeastern United States
    Personal Author:
    Lockhart, Shawn R.; Roe, Chandler C.; Engelthaler, David M.;
    Published:
    Nov 2018
    Source:
    Emerg Infect Dis. 24(11):2095-2097.
    Description:
    We conducted molecular clock analysis of whole-genome sequences from a set of autochthonous isolates of Cryptococcus gattii sensu stricto from the southeastern United States. Our analysis indicates that C. gattii arrived in the southeastern United St...
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    Filetype[PDF - 593.81 KB]
  2. Cryptococcus gattii Complex Infections in HIV-Infected Patients, Southeastern United States
    Personal Author:
    Bruner, Kaylee T.; Franco-Paredes, Carlos; Henao-Martínez, Andrés F.; Steele, Gregory M.; Chastain, Daniel B.;
    Published:
    Nov 2018
    Source:
    Emerg Infect Dis. 24(11):1998-2002.
    Description:
    Cryptococcus gattii traditionally infects immunocompetent hosts and causes devastating pulmonary or central nervous system disease. However, this infection rarely occurs in patients infected with HIV. We report 3 cases of HIV-associated C. gattii com...
    File Type:
    Filetype[PDF - 552.79 KB]
  3. Recovery of Cryptococcus gattii from an Infected Ventriculo-Peritoneal Shunt, Illinois, USA
    Personal Author:
    Moritz, Donna; Lora, Alfredo J. Mena; Blumer, Bridget; Harrington, Amanda T.;
    Published:
    Jul 2018
    Source:
    Emerg Infect Dis. 24(7):1382-1383.
    Description:
    Cryptococcus gattii is a fungal pathogen endemic in tropical and subtropical regions. Isolated cases and outbreaks have been reported in areas of North America and Europe, expanding the distribution pattern beyond warmer regions. We describe a case o...
    File Type:
    Filetype[PDF - 327.96 KB]
  4. MLST and Whole-Genome-Based Population Analysis of Cryptococcus gattii VGIII Links Clinical, Veterinary and Environmental Strains, and Reveals Divergent Serotype Specific Sub-populations and Distant Ancestors
    Personal Author:
    Firacative, Carolina; Roe, Chandler C.; Malik, Richard; Ferreira-Paim, Kennio; Escandón, Patricia; Sykes, Jane E.; Castañón-Olivares, Laura Rocío; Contreras-Peres, Cudberto; Samayoa, Blanca; Sorrell, Tania C.; Castañeda, Elizabeth; Lockhart, Shawn R.; Engelthaler, David M.; Meyer, Wieland;
    Published:
    Aug 05 2016
    Source:
    PLoS Negl Trop Dis. 10(8).
    Description:
    The emerging pathogen Cryptococcus gattii causes life-threatening disease in immunocompetent and immunocompromised hosts. Of the four major molecular types (VGI-VGIV), the molecular type VGIII has recently emerged as cause of disease in otherwise hea...
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    Filetype[PDF - 6.83 MB]
  5. Dating the Cryptococcus gattii Dispersal to the North American Pacific Northwest
    Personal Author:
    Roe, Chandler C.; Bowers, Jolene; Oltean, Hanna; DeBess, Emilio; Dufresne, Philippe J.; McBurney, Scott; Overy, David P.; Wanke, Bodo; Lysen, Colleen; Chiller, Tom; Meyer, Wieland; Thompson, George R.; Lockhart, Shawn R.; Hepp, Crystal M.; Engelthaler, David M.;
    Published:
    2018 Jan-Feb
    Source:
    mSphere. 2018; 3(1).
    Description:
    The emergence of |, previously regarded as a predominantly tropical pathogen, in the temperate climate of the North American Pacific Northwest (PNW) in 1999 prompted several questions. The most prevalent among these was the timing of the introduction...
    File Type:
    Filetype[PDF - 2.90 MB]