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Genetic Characterization of Archived Bunyaviruses and their Potential for Emergence in Australia
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May 2016
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Source: Emerg Infect Dis. 22(5):833-840.
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Alternative Title:Emerg Infect Dis
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Description:To better understand the diversity of bunyaviruses and their circulation in Australia, we sequenced 5 viruses (Gan Gan, Trubanaman, Kowanyama, Yacaaba, and Taggert) isolated and serologically identified 4 decades ago as members of the family Bunyaviridae. Gan Gan and Trubanaman viruses almost perfectly matched 2 recently isolated, purportedly novel viruses, Salt Ash and Murrumbidgee viruses, respectively. Kowanyama and Yacaaba viruses were identified as being related to members of a large clade containing pathogenic viruses. Taggert virus was confirmed as being a nairovirus; several viruses of this genus are pathogenic to humans. The genetic relationships and historical experimental infections in mice reveal the potential for these viruses to lead to disease emergence.
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Pubmed ID:27088588
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Pubmed Central ID:PMC4861517
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Volume:22
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Issue:5
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