Disseminated Infections with Talaromyces marneffei in Non-AIDS Patients Given Monoclonal Antibodies against CD20 and Kinase Inhibitors

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Chan, Jasper F.W. ; Chan, Thomas S.Y. ; Gill, Harinder ; Lam, Frank Y.F. ; Trendell-Smith, Nigel J. ; Sridhar, Siddharth ; Tse, Herman ; Lau, Susanna K.P. ; Hung, Ivan F.N. ; Yuen, Kwok-Yung ; Woo, Patrick C.Y.
• Description:
  Infections with the fungus Talaromyces (formerly Penicillium) marneffei are rare in patients who do not have AIDS. We report disseminated T. marneffei infection in 4 hematology patients without AIDS who received targeted therapy with monoclonal antibodies against CD20 or kinase inhibitors during the past 2 years. Clinicians should be aware of this emerging complication, especially in patients from disease-endemic regions.
• Subjects:
  Adult Aged Antifungal Agents Antineoplastic Agents CD20 Disseminated Infections With Talaromycesmarneffei In Non-AIDS Patients Given Monoclonal Antibodies Against CD20 And Kinase Inhibitors Fungi Humans Immunocompromised Host Kinase Inhibitors Male Middle Aged Monoclonal Antibodies Mycoses Obinutuzumab Protein Kinase Inhibitors Pyrazoles Rituximab Ruxolitinib Sorafenib Synopsis Talaromyces Talaromyces (Penicillium) Marneffei Treatment Outcome

  More +
• Source:
  Emerg Infect Dis. 21(7):1101-1106
• Pubmed ID:
  26079984
• Pubmed Central ID:
  PMC4816330
• Document Type:
  Journal Article
• Volume:
  21
• Issue:
  7
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:716bbf62ef5dadc0865fba26355fc7e391325e0bedd844285628674e788bf3bf
• Download URL:
  https://stacks.cdc.gov/view/cdc/39182/cdc_39182_DS1.pdf
• File Type:
  [PDF - 919.13 KB ]