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The Association of C-Reactive Protein and Physical Activity Among a Church-Based Population of African Americans
  • Published Date:
    Aug 2015
  • Source:
    Prev Med. 2015; 77:137-140.
Filetype[PDF - 183.12 KB]


Details:
  • Pubmed ID:
  • Pubmed Central ID:
    PMC4490070
  • Description:
    Objective

    Regular physical activity can reduce systemic inflammation and, thereby, the burden of chronic inflammatory-related conditions. This study examined whether regular physical activity, measured subjectively (Rapid Assessment of Physical Activity [RAPA]) and objectively (Bodymedia’s SenseWear® activity monitor [SWA]), is associated with inflammatory or glycemic control markers.

    Methods

    Subjects were 345 participants of the Healthy Eating and Active Living in the Spirit (HEALS) lifestyle intervention among African-American (AA) churches in South Carolina in 2009. Linear regression analyses were performed to assess the relationship between both subjectively- and objectively- measured physical activity and inflammatory markers including high sensitivity c-reactive protein (CRP), interleukin-6 (IL-6), and glycosylated hemoglobin (HbA1c).

    Results

    Those who participated in regular physical activity (RAPA) had lower CRP values compared to those who were sedentary (2.3 vs. 3.8 mg/L, p<0.01). Lower levels of CRP or IL-6 were observed among those in the highest quartile of active energy expenditure (CRP: 2.0 vs. 3.6 mg/L, p=0.01) or moderate-vigorous physical activity minutes (CRP=1.7 vs. 4.5 mg/L, p<0.01; IL-6=1.5 vs. 2.1 pg/mL, p=0.01) compared to their lowest respective quartiles as measured by the SWA.

    Conclusion

    Physical activity may improve chronic inflammation, which is a primary pathophysiological mechanism for numerous chronic disorders, especially among minority populations.

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