Neisseria meningitidis Serogroup X in Sub-Saharan Africa

Agnememel, Alain; Hong, Eva; Giorgini, Dario; Nuñez-Samudio, Viginia; Deghmane, Ala-Eddine; Taha, Muhamed-Kheir

doi:10.3201/eid2204.150653

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Neisseria meningitidis Serogroup X in Sub-Saharan Africa

Apr 2016
By Agnememel, Alain ; Hong, Eva ; Giorgini, Dario ; ...
http://dx.doi.org/10.3201/eid2204.150653
Source: Emerg Infect Dis. 22(4):698-702.

[PDF-513.88 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Agnememel, Alain ; Hong, Eva ; Giorgini, Dario ; Nuñez-Samudio, Viginia ; Deghmane, Ala-Eddine ; ... More +

Agnememel, Alain ; Hong, Eva ; Giorgini, Dario ; Nuñez-Samudio, Viginia ; Deghmane, Ala-Eddine ; Taha, Muhamed-Kheir Less -
Description:

The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.
Subjects:

[+]

Animals Clone Cells Disease Models, Animal Gene Expression Genes, Reporter Genetic Variation Genome, Bacterial High-Throughput Nucleotide Sequencing Humans Luciferases Meningitis, Meningococcal Mice Mice, Inbred BALB C Mice, Transgenic Neisseria Meningitidis Operon Optical Imaging Phylogeny Serogroup Serotyping Virulence
Source:

Emerg Infect Dis. 22(4):698-702.
Pubmed ID:

26982628
Pubmed Central ID:

PMC4806945
Document Type:

Journal Article
Place as Subject:

Europe
Location:

Europe
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:3bd1a4010086ee0dbd34e35108d98af499204d7a225d4de05707c4e50fc0a503
Download URL:

https://stacks.cdc.gov/view/cdc/38704/cdc_38704_DS1.pdf
File Type:

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