Neisseria meningitidis Serogroup X in Sub-Saharan Africa

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Agnememel, Alain ; Hong, Eva ; Giorgini, Dario ; Nuñez-Samudio, Viginia ; Deghmane, Ala-Eddine ; Taha, Muhamed-Kheir
• Description:
  The epidemiology of meningococcal disease varies by geography and time. Whole-genome sequencing of Neisseria meningitidis serogroup X isolates from sub-Saharan Africa and Europe showed that serogroup X emergence in sub-Saharan Africa resulted from expansion of particular variants within clonal complex 181. Virulence of these isolates in experimental mouse models was high.
• Subjects:
  Animals Clone Cells Disease Models, Animal Gene Expression Genes, Reporter Genetic Variation Genome, Bacterial High-Throughput Nucleotide Sequencing Humans Luciferases Meningitis, Meningococcal Mice Mice, Inbred BALB C Mice, Transgenic Neisseria Meningitidis Operon Optical Imaging Phylogeny Serogroup Serotyping Virulence

  More +
• Source:
  Emerg Infect Dis. 22(4):698-702.
• Pubmed ID:
  26982628
• Pubmed Central ID:
  PMC4806945
• Document Type:
  Journal Article
• Place as Subject:
  Europe
• Location:
  Europe
• Volume:
  22
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:3bd1a4010086ee0dbd34e35108d98af499204d7a225d4de05707c4e50fc0a503
• Download URL:
  https://stacks.cdc.gov/view/cdc/38704/cdc_38704_DS1.pdf
• File Type:
  [PDF - 513.88 KB ]