Exposure Assessment in the National Children’s Study: Introduction

Details

• Alternative Title:
  Environ Health Perspect
• Personal Author:
  Needham, Larry L. ; Özkaynak, Halûk ; Whyatt, Robin M. ; Barr, Dana B. ; Wang, Richard Y. ; Naeher, Luke ; Akland, Gerry ; Bahadori, Tina ; Bradman, Asa ; Fortmann, Roy ; Liu, L-J. Sally ; Morandi, Maria ; O’Rourke, Mary Kay ; Thomas, Kent ; Quackenboss, James ; Ryan, P. Barry ; Zartarian, Valerie
• Description:
  The science of exposure assessment is relatively new and evolving rapidly with the advancement of sophisticated methods for specific measurements at the picogram per gram level or lower in a variety of environmental and biologic matrices. Without this measurement capability, environmental health studies rely on questionnaires or other indirect means as the primary method to assess individual exposures. Although we use indirect methods, they are seldom used as stand-alone tools. Analyses of environmental and biologic samples have allowed us to get more precise data on exposure pathways, from sources to concentrations, to routes, to exposure, to doses. They also often allow a better estimation of the absorbed dose and its relation to potential adverse health outcomes in individuals and in populations. Here, we make note of various environmental agents and how best to assess exposure to them in the National Children's Study--a longitudinal epidemiologic study of children's health. Criteria for the analytical method of choice are discussed with particular emphasis on the need for long-term quality control and quality assurance measures.
• Subjects:
  Adolescent Adult Allergens Child Child, Preschool Child Welfare Environmental Exposure Environmental Monitoring Environmental Pollutants Epidemiologic Studies Female Humans Infant Infant, Newborn Inorganic Chemicals Male Maternal Exposure Organic Chemicals Pregnancy Questionnaires Research

  More +
• Source:
  Environ Health Perspect. 2005; 113(8):1076-1082.
• Document Type:
  Journal Article
• Name as Subject:
  Centers for Disease Control and Prevention (U.S.) ; National Children’s Study (U.S.) ; National Institutes of Health (U.S.) ; United States. Environmental Protection Agency.
• Place as Subject:
  United States
• Volume:
  113
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c30060f971939687ec1392bca342df30456f76caee77b7e1bdb364db4d575d01
• Download URL:
  https://stacks.cdc.gov/view/cdc/3865/cdc_3865_DS1.pdf
• File Type:
  [PDF - 127.40 KB ]