No evidence for the involvement of the argasid tick Ornithodoros faini in the enzootic maintenance of marburgvirus within Egyptian rousette bats Rousettus aegyptiacus

Schuh, Amy J.; Amman, Brian R.; Apanaskevich, Dmitry A.; Sealy, Tara K.; Nichol, Stuart T.; Towner, Jonathan S.

doi:10.1186/s13071-016-1390-z

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

No evidence for the involvement of the argasid tick Ornithodoros faini in the enzootic maintenance of marburgvirus within Egyptian rousette bats Rousettus aegyptiacus

Published Date:

Mar 05 2016

Publisher's site:

http://dx.doi.org/10.1186/s13071-016-1390-z New Site Icon

Source:

Parasit Vectors. 9.

[PDF-399.08 KB]

Details:

Alternative Title:

Parasit Vectors

Personal Author:

Schuh, Amy J. ; Amman, Brian R. ; Apanaskevich, Dmitry A. ; Sealy, Tara K. ; Nichol, Stuart T. ; ... More ▼

Description:

Background

The cave-dwelling Egyptian rousette bat (ERB; Rousettus aegyptiacus) was recently identified as a natural reservoir host of marburgviruses. However, the mechanisms of transmission for the enzootic maintenance of marburgviruses within ERBs are unclear. Previous ecological investigations of large ERB colonies inhabiting Python Cave and Kitaka Mine, Uganda revealed that argasid ticks (Ornithodoros faini) are hematophagous ectoparasites of ERBs. Yet, their potential role as transmission vectors for marburgvirus has not been sufficiently assessed.

Findings

In the present study, 3,125 O. faini were collected during April 2013 from the rock crevices of Python Cave, Uganda. None of the ticks tested positive for marburgvirus-specific RNA by Q-RT-PCR. The probability of failure to detect marburgvirus at a conservative prevalence of 0.1 % was 0.05.

Conclusions

The absence of marburgvirus RNA in O. faini suggests they do not play a significant role in the transmission and enzootic maintenance of marburgvirus within their natural reservoir host.

Subject:

[+]

Pubmed ID:

26944044

Pubmed Central ID:

PMC4779231

Document Type:

Journal Article

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	13071_2016_Article_1390.nxml	application/octet-stream
	license.txt	text/plain

No Related Documents.

You May Also Like:

Filoviruses and bats

Personal Author:

Schuh, Amy J; Amman, Brian R; Towner, Jonathan S;

Published Date:

Feb 17 2017

Source:

. 38(1):12-16.

Description:

While Reston and Lloviu viruses have never been associated with human disease, the other filoviruses cause outbreaks of hemorrhagic fever characterised by person-to-person transmission and high case fatality ratios. Cumulative evidence suggests that ...

File Type:

[PDF - 286.31 KB]
Discovery and Characterization of Bukakata orbivirus (Reoviridae:Orbivirus), a Novel Virus from a Ugandan Bat

Personal Author:

Fagre, Anna C.; Lee, Justin S.; Kityo, Robert M.; Bergren, Nicholas A.; Mossel, Eric C.; Nakayiki, Teddy; Nalikka, Betty; Nyakarahuka, Luke; Gilbert, Amy T.; Peterhans, Julian Kerbis; Crabtree, Mary B.; Towner, Jonathan S.; Amman, Brian R.; Sealy, Tara K.; Schuh, Amy J.; Nichol, Stuart T.; Lutwama, Julius J.; Miller, Barry R.; Kading, Rebekah C.;

Published Date:

March 02 2019

Source:

Viruses. 2019; 11(3)

Description:

While serological and virological evidence documents the exposure of bats to medically-important arboviruses, their role as reservoirs or amplifying hosts is less well-characterized. We describe a novel orbivirus (|) isolated from an Egyptian fruit b...

File Type:

[PDF - 3.99 MB]
Clinical, Histopathologic, and Immunohistochemical Characterization of Experimental Marburg Virus Infection in A Natural Reservoir Host, the Egyptian Rousette Bat (Rousettus aegyptiacus)

Personal Author:

Jones, Megan E.B.; Amman, Brian R.; Sealy, Tara K.; Uebelhoer, Luke S.; Schuh, Amy J.; Flietstra, Timothy; Bird, Brian H.; Coleman-McCray, JoAnn D.; Zaki, Sherif R.; Nichol, Stuart T.; Towner, Jonathan S.;

Published Date:

March 02 2019

Source:

Viruses. 2019; 11(3)

Description:

Egyptian rousette bats (|) are natural reservoir hosts of Marburg virus (MARV), and Ravn virus (RAVV; collectively called marburgviruses) and have been linked to human cases of Marburg virus disease (MVD). We investigated the clinical and pathologic ...

File Type:

[PDF - 2.64 MB]
Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera

Personal Author:

Jones, Megan E.B.; Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Zaki, Sherif R.; Nichol, Stuart T.; Towner, Jonathan S.;

Published Date:

Jun 25 2015

Source:

Viruses. 2015; 7(7):3420-3442.

Description:

The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses. We investigated the sus...

File Type:

[PDF - 1.53 MB]
Egyptian rousette bats maintain long-term protective immunity against Marburg virus infection despite diminished antibody levels

Personal Author:

Schuh, Amy J.; Amman, Brian R.; Sealy, Tara K.; Spengler, Jessica R.; Nichol, Stuart T.; Towner, Jonathan S.;

Published Date:

Aug 18 2017

Source:

Sci Rep. 7.

Description:

Although bats are natural reservoir hosts for numerous zoonotic viruses, little is known about the long-term dynamics of the host immune response following infection and how these viruses are maintained in nature. The Egyptian rousette bat (ERB) is a...

File Type:

[PDF - 1.17 MB]