Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

Hoenen, Thomas; Groseth, Allison; Rosenke, Kyle; Fischer, Robert J.; Hoenen, Andreas; Judson, Seth D.; Martellaro, Cynthia; Falzarano, Darryl; Marzi, Andrea; Squires, R. Burke; Wollenberg, Kurt R.; de Wit, Emmie; Prescott, Joseph; Safronetz, David; van Doremalen, Neeltje; Bushmaker, Trenton; Feldmann, Friederike; McNally, Kristin; Bolay, Fatorma K.; Fields, Barry; Sealy, Tara; Rayfield, Mark; Nichol, Stuart T.; Zoon, Kathryn C.; Massaquoi, Moses; Munster, Vincent J.; Feldmann, Heinz

doi:10.3201/eid2202.151796

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Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool

Published Date:

Feb 2016

Publisher's site:

http://dx.doi.org/10.3201/eid2202.151796 New Site Icon

Source:

Emerg Infect Dis. 22(2):331-334.

Language:

English

[PDF-500.67 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Hoenen, Thomas ; Groseth, Allison ; Rosenke, Kyle ; Fischer, Robert J. ; Hoenen, Andreas ; ... More ▼

Description:

Rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks provides critical scientific and public health information. However, challenges exist for exporting samples to laboratories or establishing conventional sequencers in remote outbreak regions. We successfully used a novel, pocket-sized nanopore sequencer at a field diagnostic laboratory in Liberia during the current Ebola virus outbreak.

Subject:

[+]

Pubmed ID:

26812583

Pubmed Central ID:

PMC4734547

Document Type:

Journal Article

Funding:

Intramural NIH HHS/United States

Place as Subject:

Africa, Western ; Liberia ;

Collection(s):

Emerging Infectious Diseases
CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

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