Skin Ulcers and Mortality Among Adolescents and Young Adults With Spina Bifida in South Carolina During 2000–2010

Cai, Bo; McDermott, Suzanne; Wang, Yinding; Royer, Julie A.; Mann, Joshua R.; Hardin, James W.; Ozturk, Orgul; Ouyang, Lijing

doi:10.1177/0883073815596611

i

Skin Ulcers and Mortality Among Adolescents and Young Adults With Spina Bifida in South Carolina During 2000–2010

Supporting Files

Aug 03 2015
By Cai, Bo ; McDermott, Suzanne ; Wang, Yinding ; ...

File Language:

English

Details

Alternative Title:

J Child Neurol
Personal Author:

Cai, Bo ; McDermott, Suzanne ; Wang, Yinding ; Royer, Julie A. ; Mann, Joshua R. ; Hardin, James W. ; Ozturk, Orgul ; Ouyang, Lijing
Description:

The authors investigated 48 deaths (7% death rate) among 690 adolescents and young adults with spina bifida in South Carolina during 2000-2010. The authors used Medicaid and other administrative data and a retrospective cohort design that included people with spina bifida identified using ICD-9 codes. Cox regression models with time-dependent and time-invariant covariates, and Kaplan-Meier survival curves were constructed. The authors found that 21.4% of the study group had a skin ulcer during the study period and individuals with skin ulcers had significantly higher mortality than those without ulcers (P < .0001). People who had their first skin ulcer during adolescence had higher mortality than those who had the first skin ulcer during young adulthood (P = .0002; hazard ratio = 10.70, 95% confidence interval for hazard ratio: 3.01, 38.00) and those without skin ulcers, controlling for other covariates. This study showed that age at which individuals first had a skin ulcer was associated with mortality.
Subjects:

Adolescent Female Humans Kaplan-Meier Estimate Male Proportional Hazards Models Retrospective Studies Skin Ulcer Spinal Dysraphism Young Adult
Source:

J Child Neurol. 31(3):370-377.
Pubmed ID:

26239488
Pubmed Central ID:

PMC4740267
Document Type:

Journal Article
Funding:

CC999999/Intramural CDC HHS/United States ; U01 DD000776/DD/NCBDD CDC HHS/United States ; 5U01DD000776-03/DD/NCBDD CDC HHS/United States
Place as Subject:

South Carolina
Volume:

31
Issue:

3
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:d5253ed15f0f6fe6fb5b0b078a8af6ae93806e49526938b1a3489af431f68ebc
Download URL:

https://stacks.cdc.gov/view/cdc/37868/cdc_37868_DS1.pdf
File Type:

[PDF - 411.02 KB ]

File Language:

English

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