Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2201.151384
Personal Author:
Siebrasse, Erica A. ; Nguyen, Nang L. ; Willby, Melisa J. ; Erdman, Dean D. ; Menegus, Marilyn A. ; ... More +
Siebrasse, Erica A. ; Nguyen, Nang L. ; Willby, Melisa J. ; Erdman, Dean D. ; Menegus, Marilyn A. ; Wang, David Less -
Description:
WU polyomavirus (WUPyV) was detected in a bone marrow transplant recipient with severe acute respiratory distress syndrome who died in 2001. Crystalline lattices of polyomavirus-like particles were observed in the patient's lung by electron microscopy. WUPyV was detected in the lung and other tissues by real-time quantitative PCR and identified in the lung and trachea by immunohistochemistry. A subset of WUPyV-positive cells in the lung had morphologic features of macrophages. Although the role of WUPyV as a human pathogen remains unclear, these results clearly demonstrate evidence for infection of respiratory tract tissues in this patient.
Subject:
[+]
Bone Marrow Transplantation
Child, Preschool
Female
Humans
Lung
Polyomavirus
Polyomavirus Infections
Respiratory Tract Infections
Transplant Recipients

Source:
Emerg Infect Dis. 22(1):24-31.
Pubmed ID:
26691850
Pubmed Central ID:
PMC4696717
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:4e6e483c7f23ed199cd449a85a957179dcb92ed964316aa6676edff430ea3b48
File Type:

Supporting Files

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