Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia

Assiri, Abdullah; Abedi, Glen R.; Saeed, Abdulaziz A. Bin; Abdalla, Mutwakil A.; al-Masry, Malak; Choudhry, Abdul Jamil; Lu, Xiaoyan; Erdman, Dean D.; Tatti, Kathleen; Binder, Alison M.; Rudd, Jessica; Tokars, Jerome; Miao, Congrong; Alarbash, Hussain; Nooh, Randa; Pallansch, Mark; Gerber, Susan I.; Watson, John T.

doi:10.3201/eid2201.151370

i

Multifacility Outbreak of Middle East Respiratory Syndrome in Taif, Saudi Arabia

Supporting Files Public Domain

Jan 2016
By Assiri, Abdullah ; Abedi, Glen R. ; Saeed, Abdulaziz A. Bin ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Assiri, Abdullah ; Abedi, Glen R. ; Saeed, Abdulaziz A. Bin ; Abdalla, Mutwakil A. ; al-Masry, Malak ; Choudhry, Abdul Jamil ; Lu, Xiaoyan ; Erdman, Dean D. ; Tatti, Kathleen ; Binder, Alison M. ; Rudd, Jessica ; Tokars, Jerome ; Miao, Congrong ; Alarbash, Hussain ; Nooh, Randa ; Pallansch, Mark ; Gerber, Susan I. ; Watson, John T.
Description:

Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) is a novel respiratory pathogen first reported in 2012. During September 2014-January 2015, an outbreak of 38 cases of MERS was reported from 4 healthcare facilities in Taif, Saudi Arabia; 21 of the 38 case-patients died. Clinical and public health records showed that 13 patients were healthcare personnel (HCP). Fifteen patients, including 4 HCP, were associated with 1 dialysis unit. Three additional HCP in this dialysis unit had serologic evidence of MERS-CoV infection. Viral RNA was amplified from acute-phase serum specimens of 15 patients, and full spike gene-coding sequencing was obtained from 10 patients who formed a discrete cluster; sequences from specimens of 9 patients were closely related. Similar gene sequences among patients unlinked by time or location suggest unrecognized viral transmission. Circulation persisted in multiple healthcare settings over an extended period, underscoring the importance of strengthening MERS-CoV surveillance and infection-control practices.
Subjects:

Adolescent Adult Aged Aged, 80 And Over Coronavirus Infections Cross Infection Disease Outbreaks Female Health Personnel Humans Infection Control Male Middle Aged Rna, Viral / Genetics Young Adult
Source:

Emerg Infect Dis. 22(1):32-40.
Pubmed ID:

26692003
Pubmed Central ID:

PMC4696715
Document Type:

Journal Article
Place as Subject:

Saudi Arabia
Volume:

22
Issue:

1
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:9cbcf3059fa025b4d6351242659f3fc926bc5138d77a24edc9e1818b881922ef
Download URL:

https://stacks.cdc.gov/view/cdc/37296/cdc_37296_DS1.pdf
File Type:

[PDF - 1.12 MB ]

File Language:

English

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