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Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis
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  1. Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis
    Personal Author:
    Alanio, Alexandre; Denis, Blandine; Hamane, Samia; Raffoux, Emmanuel; Peffault de Latour, Régis; Menotti, Jean; Amorim, Sandy; Touratier, Sophie; Bergeron, Anne; Bretagne, Stéphane;
    Published:
    Jan 2016
    Source:
    Emerg Infect Dis. 22(1):157-158.
    File Type:
    Filetype[PDF - 266.31 KB]
  2. Invasive Fungal Disease, Isavuconazole Treatment Failure, and Death in Acute Myeloid Leukemia Patients
    Personal Author:
    Bellanger, Anne-Pauline; Berceanu, Ana; Scherer, Emeline; Desbrosses, Yohan; Daguindau, Etienne; Rocchi, Steffi; Millon, Laurence;
    Published:
    Sep 2019
    Source:
    Emerg Infect Dis. 25(9):1778-1779
    Description:
    We present 2 fatal cases of invasive fungal disease with isavuconazole treatment failure in immunocompromised patients: one with a TR34-L98H azole-resistant Aspergillus fumigatus isolate and the other a Rhizomucor-A. fumigatus co-infection. Such pati...
    File Type:
    Filetype[PDF - 431.53 KB]
  3. Multidrug-Resistant Aspergillus fumigatus Carrying Mutations Linked to Environmental Fungicide Exposure — Three States, 2010–2017
    Personal Author:
    Beer, Karlyn D.; Farnon, Eileen C.; Jain, Seema; Jamerson, Carol; Lineberger, Sarah; Miller, Jeffrey; Berkow, Elizabeth L.; Lockhart, Shawn R.; Chiller, Tom; Jackson, Brendan R.;
    Published:
    Sep 28 2018
    Source:
    MMWR Morb Mortal Wkly Rep. 67(38):1064-1067.
    Description:
    The environmental mold Aspergillus fumigatus is the primary cause of invasive aspergillosis. In patients with high-risk conditions, including stem cell and organ transplant recipients, mortality exceeds 50%. Triazole antifungals have greatly improved...
    File Type:
    Filetype[PDF - 209.26 KB]
  4. Multiple Fungicide-Driven Alterations in Azole-Resistant Aspergillus fumigatus, Colombia, 2015
    Personal Author:
    Le Pape, Patrice; Lavergne, Rose-Anne; Morio, Florent; Alvarez-Moreno, Carlos;
    Published:
    Jan 2016
    Source:
    Emerg Infect Dis. 22(1):156-157.
    File Type:
    Filetype[PDF - 266.82 KB]
  5. Clinical Implications of Azole Resistance in Aspergillus fumigatus, the Netherlands, 2007–2009
    Personal Author:
    van der Linden, Jan W.M.; Snelders, Eveline; Kampinga, Greetje A.; Rijnders, Bart J.A.; Mattsson, Eva; Debets-Ossenkopp, Yvette J.; Van Tiel, Frank H.; Melchers, Willem J.G.; Verweij, Paul E.;
    Corporate Author:
    Kuijper
    Published:
    Oct 2011
    Source:
    Emerg Infect Dis. 17(10):1846-1854.
    Description:
    The prevalence and spread of azole resistance in clinical Aspergillus fumigatus isolates in the Netherlands are currently unknown. Therefore, we performed a prospective nationwide multicenter surveillance study to determine the effects of resistance ...
    File Type:
    Filetype[PDF - 279.34 KB]