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Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis
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  1. Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis
    Personal Author:
    Alanio, Alexandre; Denis, Blandine; Hamane, Samia; Raffoux, Emmanuel; Peffault de Latour, Régis; Menotti, Jean; Amorim, Sandy; Touratier, Sophie; Bergeron, Anne; Bretagne, Stéphane;
    Published:
    Jan 2016
    Source:
    Emerg Infect Dis. 22(1):157-158.
    File Type:
    Filetype[PDF - 266.31 KB]
  2. Multidrug-Resistant Aspergillus fumigatus Carrying Mutations Linked to Environmental Fungicide Exposure — Three States, 2010–2017
    Personal Author:
    Beer, Karlyn D.; Farnon, Eileen C.; Jain, Seema; Jamerson, Carol; Lineberger, Sarah; Miller, Jeffrey; Berkow, Elizabeth L.; Lockhart, Shawn R.; Chiller, Tom; Jackson, Brendan R.;
    Published:
    Sep 28 2018
    Source:
    MMWR Morb Mortal Wkly Rep. 67(38):1064-1067.
    Description:
    The environmental mold Aspergillus fumigatus is the primary cause of invasive aspergillosis. In patients with high-risk conditions, including stem cell and organ transplant recipients, mortality exceeds 50%. Triazole antifungals have greatly improved...
    File Type:
    Filetype[PDF - 209.26 KB]
  3. Multiple Fungicide-Driven Alterations in Azole-Resistant Aspergillus fumigatus, Colombia, 2015
    Personal Author:
    Le Pape, Patrice; Lavergne, Rose-Anne; Morio, Florent; Alvarez-Moreno, Carlos;
    Published:
    Jan 2016
    Source:
    Emerg Infect Dis. 22(1):156-157.
    File Type:
    Filetype[PDF - 266.82 KB]
  4. Clinical Implications of Azole Resistance in Aspergillus fumigatus, the Netherlands, 2007–2009
    Personal Author:
    van der Linden, Jan W.M.; Snelders, Eveline; Kampinga, Greetje A.; Rijnders, Bart J.A.; Mattsson, Eva; Debets-Ossenkopp, Yvette J.; Van Tiel, Frank H.; Melchers, Willem J.G.; Verweij, Paul E.;
    Corporate Author:
    Kuijper
    Published:
    Oct 2011
    Source:
    Emerg Infect Dis. 17(10):1846-1854.
    Description:
    The prevalence and spread of azole resistance in clinical Aspergillus fumigatus isolates in the Netherlands are currently unknown. Therefore, we performed a prospective nationwide multicenter surveillance study to determine the effects of resistance ...
    File Type:
    Filetype[PDF - 279.34 KB]
  5. An invisible threat: mutation-mediated resistance to triazole drugs in Aspergillus
    Personal Author:
    Pham, Cau D.; Lockhart, Shawn R.;
    Published:
    Dec 16 2012
    Source:
    Curr Fungal Infect Rep. 6(4):288-295.
    Description:
    Aspergillosis has emerged as an important contributor to infection-related morbidity and mortality in susceptible populations. This comes at a time when we are also seeing an increase in the vulnerable populations themselves. At the same time, some p...
    File Type:
    Filetype[PDF - 324.12 KB]