Increased Risk for ESBL-Producing Bacteria from Co-administration of Loperamide and Antimicrobial Drugs for Travelers’ Diarrhea1
Published Date:Jan 2016
Source:Emerg Infect Dis. 22(1):117-120.
Extended-spectrum Beta-lactamase–producing Enterobacteriaceae
Increased Risk For ESBL-Producing Bacteria From Co-administration Of Loperamide And Antimicrobial Drugs For Travelers’ Diarrhea
Pubmed Central ID:PMC4696706
Description:Antimicrobial drug treatment of travelers' diarrhea is known to increase the risk for colonization with extended-spectrum β-lactamase-producing Enterobacteriaceae. Among 288 travelers with travelers' diarrhea, the colonization rate without medications was 21%. For treatment with loperamide only, the rate was 20%; with antimicrobial drugs alone, 40%; and with loperamide and antimicrobial drugs, 71%.
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