Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2201.150791
Personal Author:
Baussano, Iacopo ; Lazzarato, Fulvio ; Brisson, Marc ; Franceschi, Silvia
Baussano, Iacopo ; Lazzarato, Fulvio ; Brisson, Marc ; Franceschi, Silvia Less -
Description:
Human papillomavirus (HPV) prevalence varies widely worldwide. We used a transmission model to show links between age-specific sexual patterns and HPV vaccination effectiveness. We considered rural India and the United States as examples of 2 heterosexual populations with traditional age-specific sexual behavior and gender-similar age-specific sexual behavior, respectively. We simulated these populations by using age-specific rates of sexual activity and age differences between sexual partners and found that transitions from traditional to gender-similar sexual behavior in women <35 years of age can result in increased (2.6-fold in our study) HPV16 prevalence. Our model shows that reductions in HPV16 prevalence are larger if vaccination occurs in populations before transitions in sexual behavior and that increased risk for HPV infection attributable to transition is preventable by early vaccination. Our study highlights the importance of using time-limited opportunities to introduce HPV vaccination in traditional populations before changes in age-specific sexual patterns occur.
Subject:
[+]
Epidemiologic Transition
Heterosexuality
Human Papillomavirus 16
Human Papillomavirus Vaccination At A Time Of Changing Sexual Behavior
Immunization
Papillomavirus Vaccines
Research
Sexual Behavior
Sexual Partners
Vaccination
Viruses

Source:
Emerg Infect Dis. 22(1):18-23.
Pubmed ID:
26691673
Pubmed Central ID:
PMC4696692
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:9290ca31dddf0e8717e8a3c88c1fa9cc47c746d74dcb1d0b66d10b8689c74992
File Type:

Supporting Files

• 	license.txt	txt
  	15-0791-F1.gif	gif
  	15-0791-F1.jpg	jpeg
  	15-0791-F2.gif	gif
  	15-0791-F2.jpg	jpeg
  	15-0791-Techapp-s1.pdf	pdf
  	15-0791.nxml	bin

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