Contribution of the Neighborhood Environment and Obesity to Breast Cancer Survival: The California Breast Cancer Survivorship Consortium

Details

• Alternative Title:
  Cancer Epidemiol Biomarkers Prev
• Personal Author:
  Cheng, Iona ; Shariff-Marco, Salma ; Koo, Jocelyn ; Monroe, Kristine R. ; Yang, Juan ; John, Esther M. ; Kurian, Allison W. ; Kwan, Marilyn L. ; Henderson, Brian E. ; Bernstein, Leslie ; Lu, Yani ; Sposto, Richard ; Vigen, Cheryl ; Wu, Anna H. ; Gomez, Scarlett Lin ; Keegan, Theresa H.M.
• Description:
  Little is known about neighborhood attributes that may influence opportunities for healthy eating and physical activity in relation to breast cancer mortality. We used data from the California Breast Cancer Survivorship Consortium and the California Neighborhoods Data System (CNDS) to examine the neighborhood environment, body mass index, and mortality after breast cancer. We studied 8,995 African American, Asian American, Latina, and non-Latina white women with breast cancer. Residential addresses were linked to the CNDS to characterize neighborhoods. We used multinomial logistic regression to evaluate the associations between neighborhood factors and obesity and Cox proportional hazards regression to examine associations between neighborhood factors and mortality. For Latinas, obesity was associated with more neighborhood crowding [quartile 4 (Q4) vs. Q1: OR, 3.24; 95% confidence interval (CI), 1.50-7.00]; breast cancer-specific mortality was inversely associated with neighborhood businesses (Q4 vs. Q1: HR, 0.46; 95% CI, 0.25-0.85) and positively associated with multifamily housing (Q3 vs. Q1: HR, 1.98; 95% CI, 1.20-3.26). For non-Latina whites, lower neighborhood socioeconomic status (SES) was associated with obesity [quintile 1 (Q1) vs. Q5: OR, 2.52; 95% CI, 1.31-4.84], breast cancer-specific (Q1 vs. Q5: HR, 2.75; 95% CI, 1.47-5.12), and all-cause (Q1 vs. Q5: HR, 1.75; 95% CI, 1.17-2.62) mortality. For Asian Americans, no associations were seen. For African Americans, lower neighborhood SES was associated with lower mortality in a nonlinear fashion. Attributes of the neighborhood environment were associated with obesity and mortality following breast cancer diagnosis, but these associations differed across racial/ethnic groups.
• Subjects:
  Article Body Mass Index Breast Neoplasms California California Breast Cancer Survivorship Consortium Cross-Sectional Studies Environment Female Humans Mortality Neighborhood Environment Obesity Residence Characteristics Survival Survival Rate

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• Source:
  Cancer Epidemiol Biomarkers Prev. 24(8):1282-1290.
• Pubmed ID:
  26063477
• Pubmed Central ID:
  PMC4687960
• Document Type:
  Journal Article
• Funding:
  1U58 DP000807-01/DP/NCCDPHP CDC HHS/United States ; HHSN261201000140C/PHS HHS/United States ; HHSN26120100034C/PHS HHS/United States ; HHSN26120100035C/PHS HHS/United States ; K05 CA136967/CA/NCI NIH HHS/United States ; N01-HD-3-3175/HD/NICHD NIH HHS/United States ; R01 CA054281/CA/NCI NIH HHS/United States ; R01 CA063446/CA/NCI NIH HHS/United States ; R01 CA077305/CA/NCI NIH HHS/United States ; R01 CA129059/CA/NCI NIH HHS/United States ; R01 CA54281/CA/NCI NIH HHS/United States ; R01 CA77398/CA/NCI NIH HHS/United States ; R37 CA054281/CA/NCI NIH HHS/United States ; R37CA54281/CA/NCI NIH HHS/United States ; U01 CA164973/CA/NCI NIH HHS/United States ; UM1 CA164973/CA/NCI NIH HHS/United States
• Volume:
  24
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d0bc9eda252796c6cd5087e18b3fe63dd5d69dc79adfa10c5c54224436421f5b
• Download URL:
  https://stacks.cdc.gov/view/cdc/37016/cdc_37016_DS1.pdf
• File Type:
  [PDF - 762.67 KB ]