Details:

Alternative Title:
J Occup Environ Med
Publisher's site:
http://dx.doi.org/10.1097/JOM.0b013e318255ba74
Personal Author:
Krajnak, Kristine ; Miller, G. Roger ; Waugh, Stacey ; Johnson, Claud ; Kashon, Michael L.
Krajnak, Kristine ; Miller, G. Roger ; Waugh, Stacey ; Johnson, Claud ; Kashon, Michael L. Less -
Description:
Objective

Occupational exposure to hand-transmitted vibration can result in damage to nerves and sensory loss. The goal of this study was to assess the frequency-dependent effects of repeated bouts of vibration on sensory nerve function and associated changes in nerves.

Methods

The tails of rats were exposed to vibration at 62.5, 125, or 250 Hz (constant acceleration of 49m/s2) for 10 days. The effects on sensory nerve function, nerve morphology, and transcript expression in ventral tail nerves were measured.

Results

Vibration at all frequencies had effects on nerve function and physiology. However, the effects tended to be more prominent with exposure at 250 Hz.

Conclusion

Exposure to vibration has detrimental effects on sensory nerve function and physiology. However, many of these changes are more prominent at 250-Hz exposure than at lower frequencies.


Subject:
[+]
Animals
Article
Disease Models, Animal
Male
Occupational Diseases
Rats
Rats, Sprague-Dawley
Sensory Receptor Cells
Tail
Vascular System Injuries
Vibration

Source:
J Occup Environ Med. 54(8):1010-1016.
Pubmed ID:
22785326
Pubmed Central ID:
PMC4678325
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:93657cd835364189455d4d70ae187c96fa4689069340aeab9640d4152e5f8a98
File Type:

Supporting Files

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