Successful Treatment of an Adolescent with Naegleria fowleri Primary Amebic Meningoencephalitis

Details

• Alternative Title:
  Pediatrics
• Personal Author:
  Linam, W. Matthew ; Ahmed, Mubbasheer ; Cope, Jennifer R. ; Chu, Craig ; Visvesvara, Govinda S. ; da Silva, Alexandre J. ; Qvarnstrom, Yvonne ; Green, Jerril
• Description:
  Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosine), and management of elevated intracranial pressure based on the principles of traumatic brain injury.
• Subjects:
  Amebiasis Anti-Bacterial Agents Article Central Nervous System Protozoal Infections Cerebrospinal Fluid Child Diagnosis, Differential DNA, Protozoan Female Follow-Up Studies Humans Hypothermia Magnetic Resonance Imaging Miltefosine Naegleria Fowleri Primary Amebic Meningoencephalitis

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• Source:
  Pediatrics. 135(3):e744-e748
• Pubmed ID:
  25667249
• Pubmed Central ID:
  PMC4634363
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  135
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:7c842e89af156a3ae89223c6a4863e2874b6dabd3f7f97ed7146e7388bd18ae9
• Download URL:
  https://stacks.cdc.gov/view/cdc/36415/cdc_36415_DS1.pdf
• File Type:
  [PDF - 470.15 KB ]