Effect of temperature and duration of storage on the stability of polyfluoroalkyl chemicals in human serum

Details

• Alternative Title:
  Chemosphere
• Personal Author:
  Kato, Kayoko ; Wong, Lee-Yang ; Basden, Brian J. ; Calafat, Antonia M.
• Description:
  We assessed the potential impact of temperature on the long-term stability of several polyfluoroalkyl chemicals in serum. We evaluated the concentrations of perfluorooctane sulfonate, perfluorohexane sulfonate, perfluorooctanoate and perfluorononanoate in 16 human serum samples stored at room temperature, 5 °C, -20 °C and -70 °C at several time points during an eight month period. Concentrations of the target analytes remained unchanged under all studied conditions, even when serum was kept at room temperature for 10 days.
• Subjects:
  Biomonitoring Drug Stability Drug Storage Environmental Monitoring Fluorocarbons Humans Serum Temperature
• Source:
  Chemosphere. 91(2):115-117.
• Pubmed ID:
  23232044
• Pubmed Central ID:
  PMC4629815
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  91
• Issue:
  2
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:5cff39cb403afe51dc579181da056b33172d41882863cac306cb7b016b3f528e
• Download URL:
  https://stacks.cdc.gov/view/cdc/36374/cdc_36374_DS1.pdf
• File Type:
  [PDF - 129.59 KB ]