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Guidelines for maintaining and managing the vaccine cold chain
  • Published Date:
    October 24, 2003
  • Status:
  • Source:
    MMWR. Morbidity and mortality weekly report. 2003; 52(42):1023-5.
Filetype[PDF-516.34 KB]

  • Corporate Authors:
    United States. Advisory Committee on Immunization Practices. ; American Academy of Family Physicians. ;
  • Description:
    In February 2002, the Advisory Committee on Immunization Practices (ACIP) and American Academy of Family Physicians (AAFP) released their revised General Recommendations on Immunization, which included recommendations on the storage and handling of immunobiologics. Because of increased concern over the potential for errors with the vaccine cold chain (i.e., maintaining proper vaccine temperatures during storage and handling to preserve potency), this notice advises vaccine providers of the importance of proper cold chain management practices. This report describes proper storage units and storage temperatures, outlines appropriate temperature-monitoring practices, and recommends steps for evaluating a temperature-monitoring program. The success of efforts against vaccine-preventable diseases is attributable in part to proper storage and handling of vaccines. Exposure of vaccines to temperatures outside the recommended ranges can affect potency adversely, thereby reducing protection from vaccine-preventable diseases. Good practices to maintain proper vaccine storage and handling can ensure that the full benefit of immunization is realized.

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