Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251

Details

• Alternative Title:
  J Med Primatol
• Personal Author:
  Morris, Monica ; Byrareddy, Siddappa N. ; Villinger, Francois ; Henning, Tara C. ; Butler, Katherine ; Ansari, Aftab A. ; McNicholl, Janet ; Kersh, Ellen
• Description:
  Varying susceptibility during menstrual cycling could be a factor for S(H)IV infection risk in female rhesus macaques. We retrospectively determined vaginal SIV infection time points relative to the menstrual cycle in a group of rhesus macaques (n=11) enrolled in an HIV transmission trial. Eight of nine rhesus macaques became infected around menstruation time.
• Subjects:
  Animals Article Female Macaca Mulatta Menstrual Cycle Progesterone Retrospective Studies Rhesus Macaque Simian Acquired Immunodeficiency Syndrome Simian Immunodeficiency Virus SIV Vagina

  More +
• Source:
  J Med Primatol. 44(5):301-305.
• Pubmed ID:
  26054016
• Pubmed Central ID:
  PMC4626076
• Document Type:
  Journal Article
• Funding:
  AI-098628-01/AI/NIAID NIH HHS/United States ; CC999999/Intramural CDC HHS/United States ; P51 OD11132/OD/NIH HHS/United States ; R01 AI098628/AI/NIAID NIH HHS/United States
• Volume:
  44
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:46f76906c7dc0bd67a4115e8f86b78bf86bb7d77ad98ca0030883e369403c38b
• Download URL:
  https://stacks.cdc.gov/view/cdc/36327/cdc_36327_DS1.pdf
• File Type:
  [PDF - 716.48 KB ]