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Orthobunyavirus Antibodies Among Humans in Selected Parts of the Rift Valley and Northeastern Kenya
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May 2015
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Source: Vector Borne Zoonotic Dis. 15(5):329-332.
[PDF-134.03 KB]
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Alternative Title:Vector Borne Zoonotic Dis
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Description:Ngari, Bunyamwera, Ilesha, and Germiston viruses are among the mosquito-borne human pathogens in the Orthobunyavirus genus, family Bunyaviridae, associated with febrile illness. Although the four orthobunyaviruses have been isolated from mosquito and/or tick vectors sampled from different geographic regions in Kenya, little is known of human exposure in such areas. We conducted a serologic investigation to determine whether orthobunyaviruses commonly infect humans in Kenya. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization tests in 89 (25.8%) of 345 persons tested. Multivariable analysis revealed age and residence in northeastern Kenya as risk factors. Implementation of acute febrile illness surveillance in northeastern Kenya will help to detect such infections.
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Pubmed ID:25988444
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Pubmed Central ID:PMC4666525
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