Orthobunyavirus Antibodies Among Humans in Selected Parts of the Rift Valley and Northeastern Kenya

Details

• Alternative Title:
  Vector Borne Zoonotic Dis
• Personal Author:
  Odhiambo, Collins ; Venter, Marietjie ; Swanepoel, Robert ; Sang, Rosemary
• Description:
  Ngari, Bunyamwera, Ilesha, and Germiston viruses are among the mosquito-borne human pathogens in the Orthobunyavirus genus, family Bunyaviridae, associated with febrile illness. Although the four orthobunyaviruses have been isolated from mosquito and/or tick vectors sampled from different geographic regions in Kenya, little is known of human exposure in such areas. We conducted a serologic investigation to determine whether orthobunyaviruses commonly infect humans in Kenya. Orthobunyavirus-specific antibodies were detected by plaque reduction neutralization tests in 89 (25.8%) of 345 persons tested. Multivariable analysis revealed age and residence in northeastern Kenya as risk factors. Implementation of acute febrile illness surveillance in northeastern Kenya will help to detect such infections.
• Subjects:
  Arboviruses Article Bunyaviridae Kenya Orthobunyavirus
• Source:
  Vector Borne Zoonotic Dis. 15(5):329-332.
• Pubmed ID:
  25988444
• Pubmed Central ID:
  PMC4666525
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  Kenya
• Volume:
  15
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c42323fcea9a7fc9dceafcc8f4eb4a76a068a68511b71c2e2ed10195da0dc42a
• Download URL:
  https://stacks.cdc.gov/view/cdc/36254/cdc_36254_DS1.pdf
• File Type:
  [PDF - 134.03 KB ]