Details:

Alternative Title:
Diabetes
Publisher's site:
http://dx.doi.org/10.2337/db13-1891
Personal Author:
Lawrence, Jean M. ; Imperatore, Giuseppina ; Dabelea, Dana ; Mayer-Davis, Elizabeth J. ; Linder, Barbara ; ... More +
Lawrence, Jean M. ; Imperatore, Giuseppina ; Dabelea, Dana ; Mayer-Davis, Elizabeth J. ; Linder, Barbara ; Saydah, Sharon ; Klingensmith, Georgeanna J. ; Dolan, Lawrence ; Standiford, Debra A. ; Pihoker, Catherine ; Pettitt, David J. ; Talton, Jennifer W. ; Thomas, Joan ; Bell, Ronny A. ; D’Agostino, Ralph B. Less -
Description:
The SEARCH for Diabetes in Youth Study prospectively identified youth aged <20 years with physician-diagnosed diabetes. Annual type 1 diabetes (T1D) incidence per 100,000 person-years (95% CI) overall, by age-group, and by sex were calculated for at-risk non-Hispanic white (NHW) youth from 2002 through 2009. Joinpoint and Poisson regression models were used to test for temporal trends. The age- and sex-adjusted incidence of T1D increased from 24.4/100,000 (95% CI 23.9-24.8) in 2002 to 27.4/100,000 (26.9-27.9) in 2009 (P for trend = 0.0008). The relative annual increase in T1D incidence was 2.72% (1.18-4.28) per year; 2.84% (1.12-4.58) per year for males and 2.57% (0.68-4.51) per year for females. After adjustment for sex, significant increases were found for youth aged 5-9 years (P = 0.0023), 10-14 years (P = 0.0008), and 15-19 years (P = 0.004) but not among 0-4-year-olds (P = 0.1862). Mean age at diagnosis did not change. The SEARCH study demonstrated a significant increase in the incidence of T1D among NHW youth from 2002 through 2009 overall and in all but the youngest age-group. Continued surveillance of T1D in U.S. youth to identify future trends in T1D incidence and to plan for health care delivery is warranted.
Subject:
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Adolescent Adult Child Complications Diabetes Mellitus, Type 1 Female Hispanic Americans Humans Incidence Male Prospective Studies Whites Young Adult
Source:
Diabetes. 2014; 63(11):3938-3945.
Pubmed ID:
24898146
Pubmed Central ID:
PMC4207387
Document Type:
Journal Article
Funding:
P30 DK017047/DK/NIDDK NIH HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:7cb7768da4207aab3a5e81c26407efb901088ad6e459bb5a35528a61f0fb3719
Download URL:
https://stacks.cdc.gov/view/cdc/35503/cdc_35503_DS1.pdf
File Type:

Supporting Files

• 	3938.nxml	txt
  	3938fig1.gif	gif
  	3938fig1.jpg	jpeg
  	license.txt	txt
  	supp_63_11_3938__index.html	htm
  	supp_db13-1891_DB131891SupplementaryData.pdf	pdf

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