Details:

Alternative Title:
Arthritis Rheumatol
Publisher's site:
http://dx.doi.org/10.1002/art.38239
Personal Author:
Lim, S. Sam ; Bayakly, A. Rana ; Helmick, Charles G. ; Gordon, Caroline ; Easley, Kirk ; ... More +
Lim, S. Sam ; Bayakly, A. Rana ; Helmick, Charles G. ; Gordon, Caroline ; Easley, Kirk ; Drenkard, Cristina Less -
Description:
Objective

The Georgia Lupus Registry is a population-based registry designed to improve our ability to estimate incidence and prevalence of systemic lupus erythematosus (SLE) in a large population.

Methods

Potential cases were identified from multiple sources during the years 2002 through 2004. Cases were defined by the American College of Rheumatology (ACR) Criteria for SLE or a combined definition. Age-standardized rates were determined and stratified by race and sex. With capture-recapture analyses, we estimated the under-ascertainment of cases.

Results

Using the ACR case definition, the overall crude and age-adjusted incidence rate was 5.6/100,000, with capture-recapture and combined definition rates being slightly higher. The age-adjusted incidence rate for women was >5 times higher (9.2 vs. 1.8) than that for men. Black women had an incidence rate nearly 3 times higher than that for white women with a significantly higher rate in the 30 to 59 years age group. The overall crude and age-adjusted prevalence rates were 74.4 and 73/100,000, respectively. The age-adjusted prevalence rate for women was nearly 9 times higher (127.6 vs. 14.7) than that for men. Black women had very high rates (196.2). A striking difference was seen in the proportion with end-stage renal disease in prevalent cases, with a sevenfold greater involvement among blacks.

Conclusion

With more complete case finding, our incidence and prevalence rates are among the highest reported in the United States. Results continue to underscore striking gender, age, and racial disparities between blacks and whites.


Subject:
[+]
Adult
Age Factors
Female
Humans
Incidence
Lupus Erythematosus, Systemic
Male
Middle Aged
Prevalence
Racial Groups
Registries
Retrospective Studies
Sex Factors

Source:
Arthritis Rheumatol. 66(2):357-368.
Pubmed ID:
24504808
Pubmed Central ID:
PMC4617771
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States ; DP08-806/DP/NCCDPHP CDC HHS/United States ; PA03022/PHS HHS/United States
CC999999/Intramural CDC HHS/United States ; DP08-806/DP/NCCDPHP CDC HHS/United States ; PA03022/PHS HHS/United States Less -
Place as Subject:
Georgia
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:436efb88ae03fc30ebda5b2329674c01205d3a4bb1f2912426799c91ad914083
File Type:

Supporting Files

• 	nihms717928.nxml	bin
  	nihms717928f1.gif	gif
  	nihms717928f1.jpg	jpeg
  	nihms717928f2.gif	gif
  	nihms717928f2.jpg	jpeg

More +