Global age distribution of pediatric norovirus cases

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Shioda, Kayoko ; Kambhampati, Anita ; Hall, Aron J. ; Lopman, Ben A.
• Description:
  Norovirus is increasingly recognized as a major cause of acute gastroenteritis among children <5 years of age. We searched for publications that reported detailed age distributions of pediatric norovirus cases, and assessed associations between age distribution and socio-demographic factors to identify the most critical age periods to prevent norovirus cases among young children. Approximately 70% of pediatric norovirus cases occurred between 6 and 23 months of age. A younger age distribution was found in lower income countries and inpatient settings. These findings suggest that a norovirus immunization schedule completed by 6 months could have the potential to prevent about 85% of pediatric cases, while a vaccine delivered at 12 months of age would only have the potential to prevent about 50% of pediatric cases. With a younger age distribution in lower income settings, early prevention would be even more critical.
• Subjects:
  Age Distribution Article Caliciviridae Infections Child, Preschool Gastroenteritis Global Health Humans Infant Norovirus Socioeconomic Factors Vaccine Vaccines Viral Vaccines

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• Source:
  Vaccine. 33(33):4065-4068.
• Pubmed ID:
  26051514
• Pubmed Central ID:
  PMC4612353
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  33
• Issue:
  33
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:339016c63170589c5bb7f9911383c9e6d8dcdab4208c917db7fd248076fb9f9d
• Download URL:
  https://stacks.cdc.gov/view/cdc/35200/cdc_35200_DS1.pdf
• File Type:
  [PDF - 457.62 KB ]