Details:

Alternative Title:
Microfluid Nanofluidics
Personal Author:
Zhu, Taotao ; Cheng, Rui ; Lee, Sarah A. ; Rajaraman, Eashwar ; Eiteman, Mark A. ; ... More +
Zhu, Taotao ; Cheng, Rui ; Lee, Sarah A. ; Rajaraman, Eashwar ; Eiteman, Mark A. ; Querec, Troy D. ; Unger, Elizabeth R. ; Mao, Leidong Less -
Description:
A new sorting scheme based on ferrofluid hydrodynamics (ferrohydrodynamics) was used to separate mixtures of particles and live cells simultaneously. Two species of cells, including | and |, as well as fluorescent polystyrene microparticles were studied for their sorting throughput and efficiency. Ferrofluids are stable magnetic nanoparticles suspensions. Under external magnetic fields, magnetic buoyancy forces exerted on particles and cells lead to size-dependent deflections from their laminar flow paths and result in spatial separation. We report the design, modeling, fabrication and characterization of the sorting device. This scheme is simple, low-cost and label-free compared to other existing techniques.
Subjects:
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Article Cell Sorting Continuous-flow Ferrofluid Ferrohydrodynamics Microfluidics
Source:
Microfluid Nanofluidics. 13(4):645-654
Pubmed ID:
26430394
Pubmed Central ID:
PMC4587988
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHSUnited States/
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:313c96500366dd0399706397b72ec951b50b0d64fa6e2bda85661591a8a84823
Download URL:
https://stacks.cdc.gov/view/cdc/34737/cdc_34737_DS1.pdf
File Type:

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