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Continuous-flow Ferrohydrodynamic Sorting of Particles and Cells in Microfluidic Devices
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10 2012
Source: Microfluid Nanofluidics. 13(4):645-654
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Alternative Title:Microfluid Nanofluidics
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Description:A new sorting scheme based on ferrofluid hydrodynamics (ferrohydrodynamics) was used to separate mixtures of particles and live cells simultaneously. Two species of cells, including | and |, as well as fluorescent polystyrene microparticles were studied for their sorting throughput and efficiency. Ferrofluids are stable magnetic nanoparticles suspensions. Under external magnetic fields, magnetic buoyancy forces exerted on particles and cells lead to size-dependent deflections from their laminar flow paths and result in spatial separation. We report the design, modeling, fabrication and characterization of the sorting device. This scheme is simple, low-cost and label-free compared to other existing techniques.
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Pubmed ID:26430394
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Pubmed Central ID:PMC4587988
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