Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Spengler, Jessica R.; Chakrabarti, Ayan K.; Coleman-McCray, JoAnn D.; Martin, Brock E.; Nichol, Stuart T.; Spiropoulou, Christina F.; Bird, Brian H.

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Oct 2015
By Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; ...
Source: Emerg Infect Dis. 21(10):1816-1819

[PDF-433.47 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; Martin, Brock E. ; Nichol, Stuart T. ; ... More +

Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; Martin, Brock E. ; Nichol, Stuart T. ; Spiropoulou, Christina F. ; Bird, Brian H. Less -
Description:

To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples.
Subjects:

[+]

Animals Early Diagnosis Ebolavirus Guinea Pigs Hemorrhagic Fever, Ebola Humans Mouth Specimen Handling
Source:

Emerg Infect Dis. 21(10):1816-1819
Pubmed ID:

26401603
Pubmed Central ID:

PMC4593453
Document Type:

Journal Article
Volume:

21
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:d740e5760526e56c3954578d47a10708c7acfad8fe67a15fa8ca00d81369c99e
Download URL:

https://stacks.cdc.gov/view/cdc/34721/cdc_34721_DS1.pdf
File Type:

	15-0840-F.gif	gif
	15-0840-F.jpg	jpeg
	15-0840.nxml	xml

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