Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Spengler, Jessica R.; Chakrabarti, Ayan K.; Coleman-McCray, JoAnn D.; Martin, Brock E.; Nichol, Stuart T.; Spiropoulou, Christina F.; Bird, Brian H.

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Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Supporting Files Public Domain

Oct 2015
By Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; Martin, Brock E. ; Nichol, Stuart T. ; Spiropoulou, Christina F. ; Bird, Brian H.
Description:

To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples.
Subjects:

Animals Early Diagnosis Ebolavirus Guinea Pigs Hemorrhagic Fever, Ebola Humans Mouth Specimen Handling
Source:

Emerg Infect Dis. 21(10):1816-1819
Pubmed ID:

26401603
Pubmed Central ID:

PMC4593453
Document Type:

Journal Article
Volume:

21
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:d740e5760526e56c3954578d47a10708c7acfad8fe67a15fa8ca00d81369c99e
Download URL:

https://stacks.cdc.gov/view/cdc/34721/cdc_34721_DS1.pdf
File Type:

[PDF - 433.47 KB ]

File Language:

English

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