Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Spengler, Jessica R.; Chakrabarti, Ayan K.; Coleman-McCray, JoAnn D.; Martin, Brock E.; Nichol, Stuart T.; Spiropoulou, Christina F.; Bird, Brian H.

doi:10.3201/eid2110.150840

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Utility of Oral Swab Sampling for Ebola Virus Detection in Guinea Pig Model

Published Date:

Oct 2015

Publisher's site:

http://dx.doi.org/10.3201/eid2110.150840 New Site Icon

Source:

Emerg Infect Dis. 21(10):1816-1819.

[PDF-433.47 KB]

Details:

Personal Authors:

Spengler, Jessica R. ; Chakrabarti, Ayan K. ; Coleman-McCray, JoAnn D. ; Martin, Brock E. ; Nichol, Stuart T. ; ... More ▼

Keywords:

[+]

Pubmed ID:

26401603

Pubmed Central ID:

PMC4593453

Description:

To determine the utility of oral swabs for diagnosing infection with Ebola virus, we used a guinea pig model and obtained daily antemortem and postmortem swab samples. According to quantitative reverse transcription PCR analysis, the diagnostic value was poor for antemortem swab samples but excellent for postmortem samples.

Document Type:

Journal Article

Collection(s):

CDC Public Access
Emerging Infectious Diseases

Supporting Files:

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	15-0840.nxml	text/plain
	license.txt	text/plain

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