Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131

Johnson, Diep K. Hoang; Schiffman, Elizabeth K.; Davis, Jeffrey P.; Neitzel, David F.; Sloan, Lynne M.; Nicholson, William L.; Fritsche, Thomas R.; Steward, Christopher R.; Ray, Julie A.; Miller, Tracy K.; Feist, Michelle A.; Uphoff, Timothy S.; Franson, Joni J.; Livermore, Amy L.; Deedon, Alecia K.; Theel, Elitza S.; Pritt, Bobbi S.

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Human Infection with Ehrlichia muris–like Pathogen, United States, 2007–20131

Supporting Files Public Domain

Oct 2015
By Johnson, Diep K. Hoang ; Schiffman, Elizabeth K. ; Davis, Jeffrey P. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Johnson, Diep K. Hoang ; Schiffman, Elizabeth K. ; Davis, Jeffrey P. ; Neitzel, David F. ; Sloan, Lynne M. ; Nicholson, William L. ; Fritsche, Thomas R. ; Steward, Christopher R. ; Ray, Julie A. ; Miller, Tracy K. ; Feist, Michelle A. ; Uphoff, Timothy S. ; Franson, Joni J. ; Livermore, Amy L. ; Deedon, Alecia K. ; Theel, Elitza S. ; Pritt, Bobbi S.
Description:

An Ehrlichia muris-like (EML) pathogen was detected among 4 patients in Minnesota and Wisconsin during 2009. We characterized additional cases clinically and epidemiologically. During 2004-2013, blood samples from 75,077 patients from all 50 United States were tested by PCR from the groEL gene for Ehrlichia spp. and Anaplasma phagocytophilum. During 2007-2013, samples from 69 (0.1%) patients were positive for the EML pathogen; patients were from 5 states: Indiana (1), Michigan (1), Minnesota (33), North Dakota (3), and Wisconsin (31). Most (64%) patients were male; median age was 63 (range 15-94) years; and all 69 patients reported likely tick exposure in Minnesota or Wisconsin. Fever, malaise, thrombocytopenia, and lymphopenia were the most common symptoms. Sixteen (23%) patients were hospitalized (median 4 days); all recovered, and 96% received doxycycline. Infection with the EML pathogen should be considered for persons reporting tick exposure in Minnesota or Wisconsin.
Subjects:

Adolescent Adult Aged Aged, 80 And Over Anaplasma Phagocytophilum Anaplasmataceae Animals Female Humans Male Middle Aged Minnesota Research Serologic Tests Ticks Zoonoses
Source:

Emerg Infect Dis. 21(10):1794-1799
Pubmed ID:

26402378
Pubmed Central ID:

PMC4593436
Document Type:

Journal Article
Place as Subject:

Wisconsin
Location:

North America
Volume:

21
Issue:

10
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:3e4a1c5d1e09ecd5270c598ee02aebaf81fa4285c2c0bacdeaf787c8b8082985
Download URL:

https://stacks.cdc.gov/view/cdc/34710/cdc_34710_DS1.pdf
File Type:

[PDF - 448.66 KB ]

File Language:

English

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