Characteristics and Factors Associated with Death among Patients Hospitalized for Severe Fever with Thrombocytopenia Syndrome, South Korea, 2013

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Shin, Jaeseung ; Kwon, Donghyok ; Youn, Seung-Ki ; Park, Ji-Hyuk
• Description:
  In South Korea, nationwide surveillance for severe fever with thrombocytopenia syndrome (SFTS) began during 2013. Among 301 surveillance cases, 35 hospitalized case-patients in 25 areas were confirmed by using virologic testing, and 16 (46%) case-patients subsequently died. The SFTS cases occurred during May-November and peaked during June (9 cases, 26%). The incidence of SFTS was higher in the southern regions of South Korea. Age and neurologic symptoms, including decreased level of consciousness and slurred speech, were heavily associated with death; neurologic symptoms during the first week after disease onset were also associated with death. Although melena was common among patients who died, no other hemorrhagic manifestations were substantively more common among those who died. No effective treatments, including ribavirin, were identified. Expansion of SFTS surveillance to include the outpatient sector and development of an antibody test would enhance completeness of SFTS detection in South Korea.
• Subjects:
  Adult Aged Aged, 80 And Over Animals Bunyaviridae Infections Female Humans Incidence Male Middle Aged Phlebotomus Fever Population Surveillance`` Synopsis Thrombocytopenia Tick-Borne Diseases Ticks

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• Source:
  Emerg Infect Dis. 21(10):1704-1710
• Pubmed ID:
  26402575
• Pubmed Central ID:
  PMC4593431
• Document Type:
  Journal Article
• Place as Subject:
  Republic of Korea
• Location:
  Asia
• Volume:
  21
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:90380342b1899dbd02af50b3cdabfa0496164db56595c20df8e67a7881dc9f1f
• Download URL:
  https://stacks.cdc.gov/view/cdc/34706/cdc_34706_DS1.pdf
• File Type:
  [PDF - 460.37 KB ]