Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

Details

• Alternative Title:
  J Autism Dev Disord
• Personal Author:
  Wiggins, Lisa D. ; Levy, Susan E. ; Daniels, Julie ; Schieve, Laura ; Croen, Lisa A. ; DiGuiseppi, Carolyn ; Blaskey, Lisa ; Giarelli, Ellen ; Lee, Li-Ching ; Pinto-Martin, Jennifer ; Reynolds, Ann ; Rice, Catherine ; Rosenberg, Cordelia Robinson ; Thompson, Patrick ; Yeargin-Allsopp, Marshalyn ; Young, Lisa ; Schendel, Diana
• Description:
  This study examined the phenotypic profiles of children aged 30-68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses.
• Subjects:
  Autism Spectrum Disorder Child Child, Preschool Child Development Developmental Disabilities Female Humans Male Parents Phenotype
• Keywords:
  Autism Etiology Study To Explore Early Development Symptoms
• Source:
  J Autism Dev Disord. 45(10):3183-3194
• Pubmed ID:
  26048040
• Pubmed Central ID:
  PMC4573234
• Document Type:
  Journal Article
• Funding:
  U10 DD000180/DD/NCBDD CDC HHSUnited States/ ; U10DD000184/DD/NCBDD CDC HHSUnited States/ ; U10 DD000181/DD/NCBDD CDC HHSUnited States/ ; U10DD000181/DD/NCBDD CDC HHSUnited States/ ; U10 DD000184/DD/NCBDD CDC HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ ; U01 DD000750/DD/NCBDD CDC HHSUnited States/ ; U10DD000182/DD/NCBDD CDC HHSUnited States/ ; U10 DD000182/DD/NCBDD CDC HHSUnited States/ ; U10DD000498/DD/NCBDD CDC HHSUnited States/ ; U10DD000183/DD/NCBDD CDC HHSUnited States/ ; U01 DD001210/DD/NCBDD CDC HHSUnited States/ ; P30 ES013508/ES/NIEHS NIH HHSUnited States/ ; U01 DD000498/DD/NCBDD CDC HHSUnited States/ ; U10 DD000183/DD/NCBDD CDC HHSUnited States/ ; U10DD000180/DD/NCBDD CDC HHSUnited States/
• Volume:
  45
• Issue:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b7fc6aeff5832d50b25b5fe7bc59f3de1e4eb3373f6509a55ca6e446be6e96f0
• Download URL:
  https://stacks.cdc.gov/view/cdc/34343/cdc_34343_DS1.pdf
• File Type:
  [PDF - 542.78 KB ]