Occupational exposures among nurses and risk of spontaneous abortion

LAWSON, Christina C; ROCHELEAU, Carissa M.; WHELAN, Elizabeth A; LIVIDOTI HIBERT, Eileen N.; GRAJEWSKI, Barbara; SPIEGELMAN, Donna; RICH-EDWARDS, Janet W.

doi:10.1016/j.ajog.2011.12.030

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Occupational exposures among nurses and risk of spontaneous abortion

Published Date:

Dec 30 2011

Publisher's site:

http://dx.doi.org/10.1016/j.ajog.2011.12.030 New Site Icon

Source:

Am J Obstet Gynecol. 206(4):327.e1-327.e8.

[PDF - 222.38 KB]

Details:

Personal Authors:

LAWSON, Christina C ; ROCHELEAU, Carissa M. ; WHELAN, Elizabeth A ; LIVIDOTI HIBERT, Eileen N. ; GRAJEWSKI, Barbara ; ... More ▼

Keywords:

[+]

Pubmed ID:

22304790

Pubmed Central ID:

PMC4572732

Description:

Objective

We investigated self-reported occupational exposure to antineoplastic drugs, anesthetic gases, antiviral drugs, sterilizing agents (disinfectants), and X-rays and the risk of spontaneous abortion in U.S. nurses.

Study Design

Pregnancy outcome and occupational exposures were collected retrospectively from 8,461 participants of the Nurses’ Health Study II. Of these, 7,482 were eligible for analysis using logistic regression.

Results

Participants reported 6,707 live births, and 775 (10%) spontaneous abortions (<20 weeks). After adjusting for age, parity, shift work, and hours worked, antineoplastic drug exposure was associated with a 2-fold increased risk of spontaneous abortion, particularly with early spontaneous abortion before the 12th week, and 3.5-fold increased risk among nulliparous women. Exposure to sterilizing agents was associated with a 2-fold increased risk of late spontaneous abortion (12–20 weeks), but not with early spontaneous abortion.

Conclusion

This study suggests that certain occupational exposures common to nurses are related to risks of spontaneous abortion.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

CC999999/Intramural CDC HHS/United States

Supporting Files:

nihms524347.nxml

application/octet-stream

No Related Documents.

You May Also Like:

Spontaneous abortion, sex ratio, and paternal occupational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Personal Author:

Schnorr, T M; Lawson, C C; Whelan, E A; Dankovic, D A; Deddens, J A; Piacitelli, L A; Reefhuis, J; Sweeney, M H; Connally, L B; Fingerhut, M A;

Published:

Nov 2001

Source:

Environ Health Perspect. 109(11):1127-1132.

Description:

There is conflicting research regarding an association between fetal death and paternal exposure to Agent Orange, a phenoxy herbicide widely used in Vietnam that was contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Men who worked in the ...

File Type:

[PDF - 495.66 KB]
Occupational Exposures and Lung Cancer Risk among Minnesota Taconite Mining Workers

Personal Author:

Allen, Elizabeth M; Alexander, Bruce H; MacLehose, Richard F; Nelson, Heather H; Ryan, Andrew D; Ramachandran, Gurumurthy; Mandel, Jeffrey H;

Published:

Sep 2015

Source:

Occup Environ Med. 72(9):633-639.

Description:

Objective : To examine the association between employment duration, elongate mineral particle (EMP) exposure, and silica exposure and the risk of lung cancer in the taconite mining industry. : Methods : We conducted a nested case control study of lun...

File Type:

[PDF - 186.24 KB]
Occupational Exposures and Lung Cancer Risk among Minnesota Taconite Mining Workers

Personal Author:

Allen, Elizabeth M; Alexander, Bruce H; MacLehose, Richard F; Nelson, Heather H; Ryan, Andrew D; Ramachandran, Gurumurthy; Mandel, Jeffrey H;

Published:

May 14 2015

Source:

Occup Environ Med. 72(9):633-639.

Description:

Objective : To examine the association between employment duration, elongate mineral particle (EMP) exposure, and silica exposure and the risk of lung cancer in the taconite mining industry. : Methods : We conducted a nested case control study of lun...

File Type:

[PDF - 186.24 KB]
A Case-Control Study of Occupational Injuries for Consecutive and Cumulative Shifts Among Hospital Registered Nurses and Patient Care Associates

Personal Author:

Hopcia, Karen; Dennerlein, Jack Tigh; Hashimoto, Dean; Orechia, Terry; Sorensen, Glorian;

Published:

Sep 24 2012

Source:

Workplace Health Saf. 60(10):437-444.

Description:

Nontraditional work shifts for hospital registered nurses and patient care associates and associated injuries were examined through a case-control study. Inpatient care requires that many staff work nontraditional shifts, including nights and 12-hour...

File Type:

[PDF - 60.90 KB]
Development of a Job-Task-Exposure Matrix to assess occupational exposure to disinfectants among U.S. nurses

Personal Author:

Quinot, C; Dumas, O; Henneberger, PK; Varraso, R; Wiley, AS; Speizer, FE; Goldberg, M; Zock, JP; Camargo, CA; Le Moual, N;

Published:

Aug 26 2016

Source:

Occup Environ Med. 74(2):130-137.

Description:

Objectives : Occupational exposure to disinfectants is associated with work-related asthma, especially in healthcare workers. However, little is known about the specific products involved. To evaluate disinfectant exposures, we designed job-exposure ...

Public Access
Available on:

February 01, 2018