Occupational exposures among nurses and risk of spontaneous abortion

LAWSON, Christina C; ROCHELEAU, Carissa M.; WHELAN, Elizabeth A; LIVIDOTI HIBERT, Eileen N.; GRAJEWSKI, Barbara; SPIEGELMAN, Donna; RICH-EDWARDS, Janet W.

doi:10.1016/j.ajog.2011.12.030

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Occupational exposures among nurses and risk of spontaneous abortion

Published Date:

Dec 30 2011

Publisher's site:

http://dx.doi.org/10.1016/j.ajog.2011.12.030 New Site Icon

Source:

Am J Obstet Gynecol. 206(4):327.e1-327.e8.

[PDF-222.38 KB]

Details:

Personal Authors:

LAWSON, Christina C ; ROCHELEAU, Carissa M. ; WHELAN, Elizabeth A ; LIVIDOTI HIBERT, Eileen N. ; GRAJEWSKI, Barbara ; ... More ▼

Keywords:

[+]

Pubmed ID:

22304790

Pubmed Central ID:

PMC4572732

Description:

Objective

We investigated self-reported occupational exposure to antineoplastic drugs, anesthetic gases, antiviral drugs, sterilizing agents (disinfectants), and X-rays and the risk of spontaneous abortion in U.S. nurses.

Study Design

Pregnancy outcome and occupational exposures were collected retrospectively from 8,461 participants of the Nurses’ Health Study II. Of these, 7,482 were eligible for analysis using logistic regression.

Results

Participants reported 6,707 live births, and 775 (10%) spontaneous abortions (<20 weeks). After adjusting for age, parity, shift work, and hours worked, antineoplastic drug exposure was associated with a 2-fold increased risk of spontaneous abortion, particularly with early spontaneous abortion before the 12th week, and 3.5-fold increased risk among nulliparous women. Exposure to sterilizing agents was associated with a 2-fold increased risk of late spontaneous abortion (12–20 weeks), but not with early spontaneous abortion.

Conclusion

This study suggests that certain occupational exposures common to nurses are related to risks of spontaneous abortion.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

CC999999/Intramural CDC HHS/United States

Main Document Checksum:

[+]

Supporting Files:

nihms524347.nxml

application/octet-stream

No Related Documents.

You May Also Like:

Review of hazards to female reproductive health in veterinary practice

Personal Author:

Scheftel, Joni M.; Elchos, Brigid L.; Rubin, Carol S.; Decker, John A.;

Published:

Apr 15 2017

Source:

J Am Vet Med Assoc. 250(8):862-872.

Description:

OBJECTIVE : To review publications that address female reproductive health hazards in veterinary practice, summarize best practices to mitigate reproductive risks, and identify current knowledge gaps. : DESIGN : Systematized review. : SAMPLE : Englis...

File Type:

[PDF - 450.19 KB]
Occupational exposure to waste anesthetic gases and vapors : criteria for a recommended standard

Corporate Author:

National Institute for Occupational Safety and Health.

Published:

March 1977

Series:

Criteria for a recommended standard
DHEW publication ; no. (NIOSH) 77-140

Description:

"The NIOSH standard of a 2ppm exposure limit to halogenated anesthetics and 25ppm of nitrous-oxide (10024972) is given as well as recommendations for control procedures and work practices, medical surveillance, labeling and posting, fire and explosio...

Status:

current

File Type:

[PDF - 2.80 MB]
Reproductive and developmental hazards

Personal Author:

Welch, Laura S.; Paul, Maureen;

Corporate Author:

United States. Agency for Toxic Substances and Disease Registry.. DeLima Associates..

Published:

September 1993

Series:

Case studies in environmental medicine ; 29

Description:

Prepared by DeLima Associates, San Rafael, California, under Contract No. 205-90-0817.

File Type:

[PDF - 16.33 MB]
Miscarriage Among Flight Attendants

Personal Author:

Grajewski, Barbara; Whelan, Elizabeth A.; Lawson, Christina C.; Hein, Misty J.; Waters, Martha A.; Anderson, Jeri L.; MacDonald, Leslie A.; Mertens, Christopher J.; Tseng, Chih-Yu; Cassinelli, Rick T.; Luo, Lian;

Published:

Mar 2015

Source:

Epidemiology. 2015; 26(2):192-203.

Description:

Background : Cosmic radiation and circadian disruption are potential reproductive hazards for flight attendants. : Methods : Flight attendants from 3 US airlines in 3 cities were interviewed for pregnancy histories and lifestyle, medical, and occupat...

File Type:

[PDF - 411.35 KB]
Disease clusters; an overview

Personal Author:

Pharagood-Wade, Felicia; Swirsky, Lauren; Teran-MacIver, Maria;

Corporate Author:

United States, Agency for Toxic Substances and Disease Registry., Division of Health Education and Promotion.

Published:

August 2002

Series:

Case studies in environmental medicine

Description:

This monograph is one in a series of self-instructional publications designed to increase the primary care provider’s knowledge of hazardous substances in the environment and to aid in the evaluation of potentially exposed patients. : "ATSDR public...

File Type:

[PDF - 348.55 KB]