Details:

Alternative Title:
J Anal Toxicol
Personal Author:
Hamelin, Elizabeth I. ; Johnson, Rudolph C. ; Osterloh, John ; Thomas, Jerry ;
Hamelin, Elizabeth I. ; Johnson, Rudolph C. ; Osterloh, John ; Thomas, Jerry ; Less -
Description:
A case is presented of the attempted suicide of a 58-year-old man using castor beans. The patient came to the emergency room complaining of nausea, vomiting and diarrhea for nine hours following the ingestion of six castor beans. Urine samples were taken throughout the hospital stay and submitted to the Centers for Disease Control and Prevention for analysis of ricinine, a castor bean component. The samples were found to be positive for ricinine, with a maximum concentration of 674 µg/g-creatinine excreted approximately 23 h post-exposure. Subsequent samples demonstrated lower ricinine concentrations, with the final sample taken at 62 h post-exposure at a concentration of 135 µg/g-creatinine of ricinine. The estimated urinary excretion half-life was approximately 15 h and the recovery of ricinine in the urine over the three days was estimated to be less than 10%. The patient fully recovered with supportive care and was discharged from the hospital six days after admission.
Subject:
[+]
Alkaloids
Article
Biomarkers
Castor Bean
Diarrhea
Half-Life
Humans
Male
Middle Aged
Pyridones
Ricin
Suicide, Attempted
Treatment Outcome
Vomiting

Source:
J Anal Toxicol. 36(9):660-662.
Pubmed ID:
23014889
Pubmed Central ID:
PMC4561852
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:c37f44eadfad95c8941dc2cad114467ed077c4dec4774bda1a7b8cd083e196c0
File Type:

Supporting Files

• 	nihms719588.nxml	bin
  	nihms719588f1.gif	gif
  	nihms719588f1.jpg	jpeg
  	nihms719588f2.gif	gif
  	nihms719588f2.jpg	jpeg

More +