CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Brainstem auditory evoked potentials in children with low level cumulative lead exposure
-
2015 Jan-Feb
-
-
Source: Braz J Otorhinolaryngol. 81(1):37-43.
[PDF-419.65 KB]
Details:
-
Alternative Title:Braz J Otorhinolaryngol
-
Personal Author:
-
Description:Introduction
Earlier studies have demonstrated an auditory effect of lead exposure in children,but information on the effects of low chronic exposures needs to be further elucidated.
Objective
To investigate the effect of low chronic exposures of the auditory system in childrenwith a history of low blood lead levels, using an auditory electrophysiological test.
Methods
Contemporary cross-sectional cohort. Study participants underwent tympanometry, pure tone and speech audiometry, transient evoked otoacoustic emissions, and brainstem auditory evoked potentials, with blood lead monitoring over a period of 35.5 months. The study included 130 children, with ages ranging from 18 months to 14 years, 5 months (mean age 6years, 8 months ± 3 years, 2 months).
Results
The mean time-integrated cumulative blood lead index was 12 g/dL (SD ± 5.7, range:2.433). All participants had hearing thresholds equal to or below 20 dBHL and normal amplitudes of transient evoked otoacoustic emissions. No association was found between the absolute latencies of waves I, III, and V, the interpeak latencies I---III, III---V, and I---V, and the cumulative lead values.
Conclusion
No evidence of toxic effects from chronic low lead exposures was observed on the auditory function of children living in a lead contaminated area.
-
Subjects:
-
Source:
-
Pubmed ID:25458254
-
Pubmed Central ID:PMC4557785
-
Document Type:
-
Funding:
-
Volume:81
-
Issue:1
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
