Longitudinal spirometry among patients in a treatment program for community members with World Trade Center (WTC)-related illness

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Liu, Mengling ; Qian, Meng ; Cheng, Qinyi ; Berger, Kenneth I. ; Shao, Yongzhao ; Turetz, Meredith ; Kazeros, Angeliki ; Parsia, Sam ; Goldring, Roberta M. ; Fernandez-Beros, Maria Elena ; Marmor, Michael ; Reibman, Joan
• Description:
  Objective
  
  The course of lung function in community members exposed to World Trade Center (WTC) dust and fumes remains undefined. We studied longitudinal spirometry among patients in the WTC Environmental Health Center (WTCEHC) treatment program.
  
  Methods
  
  Observational study of 946 WTCEHC patients with repeated spirometry measures analyzed on the population as a whole and stratified by smoking status, initial spirometry pattern and WTC-related exposure category.
  
  Results
  
  Improvement in forced expiratory volume (FVC; 54.4 ml/year; 95% CI: 45.0-63.8) and forced expiratory volume in one second (FEV1; 36.8 ml/year; 95% CI: 29.3-44.3) was noted for the population as a whole. Heavy smokers did not improve. Spirometry changes differed depending on initial spirometry pattern and exposure category.
  
  Conclusions
  
  These data demonstrate spirometry improvement in select populations suggesting reversibility in airway injury and reinforcing the importance of continued treatment.
  
  
• Subjects:
  Acute Lung Injury Adult Dust Female Humans Longitudinal Studies Male Middle Aged Occupational Diseases Occupational Exposure Residence Characteristics September 11 Terrorist Attacks Smoking Spirometry

  More +
• Source:
  J Occup Environ Med. 54(10):1208-1213.
• Pubmed ID:
  22995806
• Pubmed Central ID:
  PMC3665157
• Document Type:
  Journal Article
• Funding:
  1E11OH009630/OH/NIOSH CDC HHS/United States ; ES00260/ES/NIEHS NIH HHS/United States ; T32 ES007267/ES/NIEHS NIH HHS/United States ; T32 ES07267/ES/NIEHS NIH HHS/United States
• Volume:
  54
• Issue:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:49fb5f147e953677b6049f54e878933de95e256bdc7d3503fbf324a1eab30b2c
• Download URL:
  https://stacks.cdc.gov/view/cdc/33569/cdc_33569_DS1.pdf
• File Type:
  [PDF - 535.16 KB ]