Details:

Alternative Title:
J Occup Environ Med
Publisher's site:
http://dx.doi.org/10.1097/JOM.0b013e31826bb78e
Personal Author:
Liu, Mengling ; Qian, Meng ; Cheng, Qinyi ; Berger, Kenneth I. ; Shao, Yongzhao ; ... More +
Liu, Mengling ; Qian, Meng ; Cheng, Qinyi ; Berger, Kenneth I. ; Shao, Yongzhao ; Turetz, Meredith ; Kazeros, Angeliki ; Parsia, Sam ; Goldring, Roberta M. ; Fernandez-Beros, Maria Elena ; Marmor, Michael ; Reibman, Joan Less -
Description:
Objective

The course of lung function in community members exposed to World Trade Center (WTC) dust and fumes remains undefined. We studied longitudinal spirometry among patients in the WTC Environmental Health Center (WTCEHC) treatment program.

Methods

Observational study of 946 WTCEHC patients with repeated spirometry measures analyzed on the population as a whole and stratified by smoking status, initial spirometry pattern and WTC-related exposure category.

Results

Improvement in forced expiratory volume (FVC; 54.4 ml/year; 95% CI: 45.0-63.8) and forced expiratory volume in one second (FEV1; 36.8 ml/year; 95% CI: 29.3-44.3) was noted for the population as a whole. Heavy smokers did not improve. Spirometry changes differed depending on initial spirometry pattern and exposure category.

Conclusions

These data demonstrate spirometry improvement in select populations suggesting reversibility in airway injury and reinforcing the importance of continued treatment.


Subject:
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Acute Lung Injury
Adult
Article
Dust
Female
Humans
Longitudinal Studies
Male
Middle Aged
Occupational Diseases
Occupational Exposure
Residence Characteristics
September 11 Terrorist Attacks
Smoking
Spirometry

Source:
J Occup Environ Med. 54(10):1208-1213.
Pubmed ID:
22995806
Pubmed Central ID:
PMC3665157
Document Type:
Journal Article
Funding:
1E11OH009630/OH/NIOSH CDC HHS/United States ; ES00260/ES/NIEHS NIH HHS/United States ; T32 ES007267/ES/NIEHS NIH HHS/United States ; T32 ES07267/ES/NIEHS NIH HHS/United States
1E11OH009630/OH/NIOSH CDC HHS/United States ; ES00260/ES/NIEHS NIH HHS/United States ; T32 ES007267/ES/NIEHS NIH HHS/United States ; T32 ES07267/ES/NIEHS NIH HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:49fb5f147e953677b6049f54e878933de95e256bdc7d3503fbf324a1eab30b2c
File Type:

Supporting Files

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