Head and Neck Cancer in World Trade Center Responders: A Case Series

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Graber, Judith M. ; Chuang, Connie T. ; Ward, Carolyn L. ; Black, Kathleen ; Udasin, Iris G.
• Description:
  Objective
  
  To report on cases of head and neck cancer (HNC) among World Trade Center (WTC) responders participating in the WTC Health Program and seen at Rutgers WTC Center of Clinical Excellence.
  
  Methods
  
  Medical records were abstracted by two clinical reviewers and discrepancies resolved. Cases were defined as WTC responders diagnosed with HNC between 9/12/2005 and 12/31/2016.
  
  Results
  
  Sixteen HNC patients met the case definition, most (13) arrived at the WTC location on 9/11 or within the following 2 days and half worked in law enforcement during the 9/1 response.
  
  Conclusions
  
  An association between HNC and WTC exposure is biologically plausible and should be further investigated. Research to enumerate the risk factor profile for these cancers may contribute to understanding mechanisms by which WTC exposure can contribute to carcinogenesis and to prevention and early detection strategies.
  
  
• Keywords:
  Adult Aged Emergency Responders Female Humans Laryngeal Neoplasms Male Middle Aged Mouth Neoplasms Oropharyngeal Neoplasms Retrospective Studies Risk Factors September 11 Terrorist Attacks Squamous Cell Carcinoma Of Head And Neck

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• Source:
  J Occup Environ Med. 60(9):e439-e444
• Pubmed ID:
  29933317
• Pubmed Central ID:
  PMC6131053
• Document Type:
  Journal Article
• Funding:
  U01 OH011322/OH/NIOSH CDC HHSUnited States/ ; U10 OH008239/OH/NIOSH CDC HHSUnited States/ ; P30 ES005022/ES/NIEHS NIH HHSUnited States/ ; T42OH008422/ACL/ACL HHSUnited States/ ; U01OH011322/ACL/ACL HHSUnited States/
• Place as Subject:
  United States
• Volume:
  60
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c01d4959735334d136ba9e03de19812c63b3ebab75075c52ce8c1c4045d8bb9f
• Download URL:
  https://stacks.cdc.gov/view/cdc/58864/cdc_58864_DS1.pdf
• File Type:
  [PDF - 85.81 KB ]