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Label-Free Polypeptide-Based Enzyme Detection Using a Graphene-Nanoparticle Hybrid Sensor
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Published Date:
September 07 2012
Source:Adv Mater. 2012; 24(45):6081-6087Language:English
[PDF-2.51 MB]
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Alternative Title:Adv Mater
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Description:A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface.
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Pubmed ID:22961629
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Pubmed Central ID:PMC3626444
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