Details:

Alternative Title:
Adv Mater
Personal Author:
Myung, Sung ; Yin, Perry T. ; Kim, Cheoljin ; Park, Jaesung ; Solanki, Aniruddh ; ... More +
Myung, Sung ; Yin, Perry T. ; Kim, Cheoljin ; Park, Jaesung ; Solanki, Aniruddh ; Reyes, Pavel Ivanoff ; Lu, Yicheng ; Kim, Kwang S. ; Lee, Ki-Bum Less -
Description:
A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface.
Subject:
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Article
Biosensing Techniques
Carboxypeptidase B
Conductometry
Enzyme Activation
Equipment Design
Equipment Failure Analysis
Graphite
Nanoparticles
Nanotechnology
Peptides
Staining And Labeling

Source:
Adv Mater. 2012; 24(45):6081-6087
Pubmed ID:
22961629
Pubmed Central ID:
PMC3626444
Document Type:
Journal Article
Funding:
DP2 OD006462/OD/NIH HHS/United States ; T32 GM008339/GM/NIGMS NIH HHS/United States ; 1DP20D006462-01/DP/NCCDPHP CDC HHS/United States
DP2 OD006462/OD/NIH HHS/United States ; T32 GM008339/GM/NIGMS NIH HHS/United States ; 1DP20D006462-01/DP/NCCDPHP CDC HHS/United States Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:4bc2d40dce75f3ef4207476fee20319471756e14a02bcd60be9bc9d70fc03566
File Type:

Supporting Files

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