Label-Free Polypeptide-Based Enzyme Detection Using a Graphene-Nanoparticle Hybrid Sensor

Myung, Sung; Yin, Perry T.; Kim, Cheoljin; Park, Jaesung; Solanki, Aniruddh; Reyes, Pavel Ivanoff; Lu, Yicheng; Kim, Kwang S.; Lee, Ki-Bum

doi:10.1002/adma.201202961

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Label-Free Polypeptide-Based Enzyme Detection Using a Graphene-Nanoparticle Hybrid Sensor

Published Date:

Sep 07 2012

Publisher's site:

http://dx.doi.org/10.1002/adma.201202961 New Site Icon

Source:

Adv Mater. 2012; 24(45):6081-6087.

[PDF-2.51 MB]

Details:

Alternative Title:

Adv Mater

Personal Author:

Myung, Sung ; Yin, Perry T. ; Kim, Cheoljin ; Park, Jaesung ; Solanki, Aniruddh ; ... More ▼

Description:

A graphene-nanoparticle (NP) hybrid biosensor that utilizes an electrical hysteresis change to detect the enzymatic activity and concentration of Carboxypeptidase B was developed. The results indicate that the novel graphene-NP hybrid biosensor, utilizing electrical hysteresis, has the ability to detect concentrations of targeted enzyme on the micromolar scale. Furthermore, to the knowledge of the authors, this is the first demonstration of a graphene-based biosensor that utilizes a hysteresis change resulting from metallic NPs assembled on a graphene surface.

Subject:

[+]

Pubmed ID:

22961629

Pubmed Central ID:

PMC3626444

Document Type:

Journal Article

Funding:

1DP20D006462-01/DP/NCCDPHP CDC HHS/United States ; DP2 OD006462/OD/NIH HHS/United States ; T32 GM008339/GM/NIGMS NIH HHS/United States ;

Collection(s):

CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	nihms455125f4.gif	image/gif
	nihms455125f4.jpg	image/jpeg
	NIHMS455125-supplement-Supplementary_DATA.pdf	application/pdf
	nihms455125.nxml	text/plain
	nihms455125f1.gif	image/gif
	nihms455125f1.jpg	image/jpeg
	nihms455125f2.gif	image/gif
	nihms455125f2.jpg	image/jpeg
	nihms455125f3.gif	image/gif
	nihms455125f3.jpg	image/jpeg

No Related Documents.

You May Also Like:

Design, Synthesis, and Characterization of Graphene–Nanoparticle Hybrid Materials for Bioapplications

Personal Author:

Yin, Perry T.; Shah, Shreyas; Chhowalla, Manish; Lee, Ki-Bum;

Published Date:

Feb 18 2015

Source:

Chem Rev. 115(7):2483-2531.

File Type:

[PDF - 3.48 MB]
3D Graphene Oxide-encapsulated Gold Nanoparticles to Detect Neural Stem Cell Differentiation

Personal Author:

Kim, Tae-Hyung; Lee, Ki-Bum; Choi, Jeong-Woo;

Published Date:

Aug 12 2013

Source:

Biomaterials. 2013; 34(34):8660-8670.

Description:

Monitoring of stem cell differentiation and pluripotency is an important step for the practical use of stem cells in the field of regenerative medicine. Hence, a new non-destructive detection tool capable of in situ monitoring of stem cell differenti...

File Type:

[PDF - 1.37 MB]
Real-Time Monitoring of ATP-Responsive Drug Release Using Mesoporous-Silica-Coated Multicolor Upconversion Nanoparticles

Personal Author:

Lai, Jinping; Shah, Birju P.; Zhang, Yixiao; Yang, Letao; Lee, Ki-Bum;

Published Date:

Apr 15 2015

Source:

ACS Nano. 9(5):5234-5245.

Description:

Stimuli-responsive drug delivery vehicles have garnered immense interest in recent years due to unparalleled progress made in material science and nanomedicine. However, the development of stimuli-responsive devices with integrated real-time monitori...

File Type:

[PDF - 1.45 MB]
Toward the Responsible Development and Commercialization of Sensor Nanotechnologies

Personal Author:

Fadel, Tarek R.; Farrell, Dorothy F.; Friedersdorf, Lisa E.; Griep, Mark H.; Hoover, Mark D.; Meador, Michael A.; Meyyappan, M.;

Published Date:

Feb 25 2016

Source:

ACS Sens. 1(3):207-216.

Description:

Nanotechnology-enabled sensors (or nanosensors) will play an important role in enabling the progression toward ubiquitous information systems as the Internet of Things (IoT) emerges. Nanosensors offer new, miniaturized solutions in physiochemical and...

File Type:

[PDF - 1.01 MB]
3-D Printed Adjustable Microelectrode Arrays for Electrochemical Sensing and Biosensing

Personal Author:

Yang, Haipeng; Rahman, Taibur; Du, Dan; Panat, Rahul; Lin, Yuehe;

Published Date:

Jul 2016

Source:

Sens Actuators B Chem. 230:600-606

Description:

Printed Electronics has emerged as an important fabrication technique that overcomes several shortcomings of conventional lithography and provides custom rapid prototyping for various sensor applications. In this work, silver microelectrode arrays (M...

File Type:

[PDF - 748.20 KB]