Cerebrospinal Fluid Findings in Children with Fever-Associated Status Epilepticus; Results of the Febrile Status Epilepticus (FEBSTAT) Study

Details

• Alternative Title:
  J Pediatr
• Personal Author:
  Frank, L Matthew ; Shinnar, Shlomo ; Hesdorffer, Dale C ; Shinnar, Ruth C ; Pellock, John M ; Gallentine, William ; Nordli, Douglas R ; Epstein, Leon G ; Moshe, Solomon L ; Lewis, Darrell V ; Sun, Shumei
• Description:
  This prospective multicenter study of 200 patients with fever-associated status epilepticus (FSE), of whom 136 underwent a nontraumatic lumbar puncture, confirms that FSE rarely causes cerebrospinal fluid (CSF) pleocytosis. CSF glucose and protein levels were unremarkable. Temperature, age, seizure focality, and seizure duration did not affect results. CSF pleocytosis should not be attributed to FSE.
• Subjects:
  Article Biomarkers Cerebrospinal Fluid Proteins Child Glucose Humans Leukocytes Leukocytosis Prospective Studies Seizures, Febrile Spinal Puncture Status Epilepticus

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• Source:
  J Pediatr. 2012; 161(6):1169-1171.e1
• Pubmed ID:
  22985722
• Pubmed Central ID:
  PMC3504634
• Document Type:
  Journal Article
• Funding:
  1U01HL101064/HL/NHLBI NIH HHS/United States ; 5U01NS04911/NS/NINDS NIH HHS/United States ; NS045911/NS/NINDS NIH HHS/United States ; MM1002/PHS HHS/United States ; NS31146/NS/NINDS NIH HHS/United States ; NS078419/NS/NINDS NIH HHS/United States ; DP002209/DP/NCCDPHP CDC HHS/United States ; 1UL1RR031990/RR/NCRR NIH HHS/United States ; R01NS043209/NS/NINDS NIH HHS/United States ; 2R01HL040619/HL/NHLBI NIH HHS/United States ; NS20253/NS/NINDS NIH HHS/United States ; NS45911/NS/NINDS NIH HHS/United States ; NS043209/NS/NINDS NIH HHS/United States ; R01 NS043209/NS/NINDS NIH HHS/United States ; NS43209/NS/NINDS NIH HHS/United States ; 1R01HD060913/HD/NICHD NIH HHS/United States ; NS 053998/NS/NINDS NIH HHS/United States ; R37 NS043209/NS/NINDS NIH HHS/United States ; R01HD038356/HD/NICHD NIH HHS/United States ; 7R01DK071485/DK/NIDDK NIH HHS/United States ; NS 066929/NS/NINDS NIH HHS/United States ; HD042823/HD/NICHD NIH HHS/United States ; 1U10NS077308/NS/NINDS NIH HHS/United States ; NS 43209/NS/NINDS NIH HHS/United States ; UL1 RR025759/RR/NCRR NIH HHS/United States ; NS 045911/NS/NINDS NIH HHS/United States
• Volume:
  161
• Issue:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:95a8b900d5acccace9de140f7579f6a7b31cb7b288d0e38625e71ae6bc828906
• Download URL:
  https://stacks.cdc.gov/view/cdc/33477/cdc_33477_DS1.pdf
• File Type:
  [PDF - 174.97 KB ]