Early-life trauma is associated with rapid eye movement sleep fragmentation among military veterans

Details

• Alternative Title:
  Biol Psychol
• Personal Author:
  Insana, Salvatore P. ; Kolko, David J. ; Germain, Anne
• Description:
  The role of sleep in the relations between early-life trauma and the development of adverse psychological trajectories is relatively unknown and was the primary aim of the present study. Military veterans were evaluated for posttraumatic stress disorder, combat exposure, trauma history, sleep quality, disruptive nocturnal behaviors, and a subsample completed overnight polysomnography that yielded objectively measured sleep parameters. When relevant variables were controlled, increased earlier-life traumatic event exposure was associated with increased rapid-eye-movement sleep (REMs) fragmentation, and increased REMs fragmentation was associated with increased later-life disruptive nocturnal behaviors. REMs fragmentation carried an indirect relation between earlier-life trauma and later-life disruptive nocturnal behaviors. Objectively measured sleep parameters were used to describe REMs fragmentation physiology. The current findings elucidate the important role that earlier-life trauma exposure may have in the development of REM sleep physiology, and how this altered sleep physiology may have dynamic influences on subsequent posttraumatic stress symptoms in adulthood.
• Keywords:
  Adult Combat Development Disease Progression Fear Female Humans Male Middle Aged Polysomnography Psychiatric Status Rating Scales PTSD Sleep Sleep, REM Sleep Deprivation Stress Disorders, Traumatic Surveys And Questionnaires Time Factors Translational Trauma Veterans

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• Source:
  Biol Psychol. 2012; 89(3):570-579
• Pubmed ID:
  22266135
• Pubmed Central ID:
  PMC3299844
• Document Type:
  Journal Article
• Funding:
  UL1 TR000005/TR/NCATS NIH HHSUnited States/ ; R34 MH080696/MH/NIMH NIH HHSUnited States/ ; T32 HL082610/HL/NHLBI NIH HHSUnited States/ ; R34 MH-080696-03/MH/NIMH NIH HHSUnited States/ ; UL1RR024153/RR/NCRR NIH HHSUnited States/ ; T32 HL-082610-04/HL/NHLBI NIH HHSUnited States/ ; UL1 RR024153-05/RR/NCRR NIH HHSUnited States/ ; R21 MH083035-02/MH/NIMH NIH HHSUnited States/ ; T32 HL082610-05/HL/NHLBI NIH HHSUnited States/ ; UL1 RR024153/RR/NCRR NIH HHSUnited States/ ; PR054093/PR/OCPHP CDC HHSUnited States/ ; R21 MH083035/MH/NIMH NIH HHSUnited States/ ; R21 MH-083035-02/MH/NIMH NIH HHSUnited States/ ; R34 MH080696-03/MH/NIMH NIH HHSUnited States/
• Volume:
  89
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d8356d681eec5ab16f9effd5d696cf9c78f3a41204061670b302ad4ef7152e07
• Download URL:
  https://stacks.cdc.gov/view/cdc/33323/cdc_33323_DS1.pdf
• File Type:
  [PDF - 1.06 MB ]