Lymphoid malignancies in US Asians: incidence rate differences by birthplace and acculturation

Clarke, Christina A.; Glaser, Sally L.; Gomez, Scarlett L.; Wang, Sophia S.; Keegan, Theresa H.; Yang, Juan; Chang, Ellen T.

doi:10.1158/1055-9965.EPI-11-0038

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Lymphoid malignancies in US Asians: incidence rate differences by birthplace and acculturation

Published Date:

Apr 14 2011

Publisher's site:

http://dx.doi.org/10.1158/1055-9965.EPI-11-0038 New Site Icon

Source:

Cancer Epidemiol Biomarkers Prev. 20(6):1064-1077.

[PDF - 97.49 KB]

Details:

Personal Authors:

Clarke, Christina A. ; Glaser, Sally L. ; Gomez, Scarlett L. ; Wang, Sophia S. ; Keegan, Theresa H. ; ... More ▼

Keywords:

[+]

Pubmed ID:

21493873

Pubmed Central ID:

PMC3111874

Description:

Background

Malignancies of the lymphoid cells, including non-Hodgkin lymphomas (NHLs), Hodgkin lymphoma (HL) and multiple myeloma (MM), occur at much lower rates in Asians than other racial/ethnic groups in the United States (US). It remains unclear whether these deficits are explained by genetic or environmental factors. To better understand environmental contributions, we examined incidence patterns of lymphoid malignancies among populations characterized by ethnicity, birthplace, and residential neighborhood socioeconomic status (SES) and ethnic enclave status.

Methods

We obtained data regarding all Asian patients diagnosed with lymphoid malignancies between 1988 and 2004 from the California Cancer Registry and neighborhood characteristics from US Census data.

Results

While incidence rates of most lymphoid malignancies were lower among Asian than white populations, only follicular lymphoma (FL), chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), and nodular sclerosis (NS) HL rates were statistically significantly lower among foreign-born than US-born Asians, with incidence rate ratios ranging from 0.34 to 0.87. Rates of CLL/SLL and NS HL were also lower among Asian women living in ethnic enclaves or lower-SES neighborhoods than those living elsewhere. Conclusions: These observations support strong roles of environmental factors in the causation of FL, CLL/SLL, and NS HL.

Impact

Studying specific lymphoid malignancies in US Asians may provide valuable insight towards understanding their environmental causes.

Document Type:

Journal Article

Collection(s):

CDC Public Access

Funding:

1U58DP00807-01/DP/NCCDPHP CDC HHS/United States
N01 PC035136-21-0-0/PC/NCI NIH HHS/United States
R01-CA121052/CA/NCI NIH HHS/United States
R01-ES015552/ES/NIEHS NIH HHS/United States

Supporting Files:

NIHMS288200-supplement-1.docx	application/vnd.openxmlformats-officedocument.wordprocessingml.document
nihms288200.nxml	text/plain

No Related Documents.

You May Also Like:

Association of birthplace and self-reported hypertension by racial/ethnic groups among US adults – National Health Interview Survey, 2006–2010

Personal Author:

Fang, Jing; Ayala, Carma; Loustalot, Fleetwood;

Published:

Dec 2012

Source:

J Hypertens. 30(12):2285-2292.

Description:

Background : Over the past few decades, the proportion of US adults who were foreign-born has been increasing, as has the overall prevalence of hypertension. Here we compared the prevalence of self-reported hypertension among native-born adults with ...

File Type:

[PDF - 895.23 KB]
Differences in Food and Beverage Marketing Policies and Practices in US School Districts, by Demographic Characteristics of School Districts, 2012

Personal Author:

Merlo, Caitlin L.; Michael, Shannon; Brener, Nancy D.; Coffield, Edward; Kingsley, Beverly S.; Zytnick, Deena; Blanck, Heidi;

Published:

Dec 15 2016

Source:

Prev Chronic Dis. 13.

Description:

Introduction : Foods and beverages marketed in schools are typically of poor nutritional value. School districts may adopt policies and practices to restrict marketing of unhealthful foods and to promote healthful choices. Students’ exposure to mar...

File Type:

[PDF - 365.22 KB]
Accounting for differences in healthcare utilization and expenditures among US males with haemophilia by type of health insurance

Personal Author:

Guh, S.; Grosse, S.D.; Ullman, M.; Soucie, J. M.;

Published:

Feb 02 2017

Source:

Haemophilia. 23(2):e147-e151.

Public Access
Available on:

March 01, 2018
Acculturation and the Prevalence of Diabetes in US Latino Adults, National Health and Nutrition Examination Survey 2007–2010

Personal Author:

O’Brien, Matthew J.; Alos, Victor A.; Davey, Adam; Bueno, Angeli; Whitaker, Robert C.;

Published:

Oct 09 2014

Source:

Prev Chronic Dis. 11.

Description:

Introduction : US Latinos are growing at the fastest rate of any racial/ethnic group in the United States and have the highest lifetime risk of diabetes. Acculturation may increase the risk of diabetes among all Latinos, but this hypothesis has not b...

File Type:

[PDF - 376.45 KB]
The Relationship Between Area Poverty Rate and Site-Specific Cancer Incidence in the United States

Personal Author:

Boscoe, Francis P; Johnson, Christopher J; Sherman, Recinda L; Stinchcomb, David G; Lin, Ge; Henry, Kevin A;

Published:

May 27 2014

Source:

Cancer. 2014; 120(14):2191-2198.

Description:

BACKGROUND : The relationship between socioeconomic status and cancer incidence in the United States has not traditionally been a focus of population-based cancer surveillance systems. : METHODS : Nearly 3 million tumors diagnosed between 2005 and 20...

File Type:

[PDF - 238.17 KB]