Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Lee, Meng-Rui ; Sheng, Wang-Huei ; Hung, Chien-Ching ; Yu, Chong-Jen ; Lee, Li-Na ; ... More +
Lee, Meng-Rui ; Sheng, Wang-Huei ; Hung, Chien-Ching ; Yu, Chong-Jen ; Lee, Li-Na ; Hsueh, Po-Ren Less -
Description:
Mycobacterium abscessus complex comprises a group of rapidly growing, multidrug-resistant, nontuberculous mycobacteria that are responsible for a wide spectrum of skin and soft tissue diseases, central nervous system infections, bacteremia, and ocular and other infections. M. abscessus complex is differentiated into 3 subspecies: M. abscessus subsp. abscessus, M. abscessus subsp. massiliense, and M. abscessus subsp. bolletii. The 2 major subspecies, M. abscessus subsp. abscessus and M. abscessus subsp. massiliense, have different erm(41) gene patterns. This gene provides intrinsic resistance to macrolides, so the different patterns lead to different treatment outcomes. M. abscessus complex outbreaks associated with cosmetic procedures and nosocomial transmissions are not uncommon. Clarithromycin, amikacin, and cefoxitin are the current antimicrobial drugs of choice for treatment. However, new treatment regimens are urgently needed, as are rapid and inexpensive identification methods and measures to contain nosocomial transmission and outbreaks.
Subject:
[+]
Anti-Bacterial Agents
Bacteria
Clinical Disease
Communicable Diseases, Emerging
Cosmetic Procedures
Drug Resistance, Bacterial
Global Health
Humans
Identification Methods
Multidrug Resistant
Mycobacteria
Mycobacterium
Mycobacterium Abscessus
Mycobacterium Abscessus Complex
Mycobacterium Abscessus Complex Infections In Humans
Mycobacterium Bolletii
Mycobacterium Infections
Mycobacterium Massiliense
Nomenclature
Nontuberculous
Nosocomial
Outbreaks
Synopsis
Taxonomy
Transmission

Source:
Emerg Infect Dis. 21(9):1638-1646
Pubmed ID:
26295364
Pubmed Central ID:
PMC4550155
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:e8092419688585aae55a41c7ffc26a79d2ece54278ff65f84e4c65a1b63f30fd
File Type:

Supporting Files

• 	14-1634-F5.gif	gif
  	14-1634-F5.jpg	jpeg
  	14-1634.nxml	xml
  	14-1634-F1.gif	gif
  	14-1634-F1.jpg	jpeg
  	14-1634-F2.gif	gif
  	14-1634-F2.jpg	jpeg
  	14-1634-F3.gif	gif
  	14-1634-F3.jpg	jpeg
  	14-1634-F4.gif	gif
  	14-1634-F4.jpg	jpeg

More +