Acute myeloid leukemia risk by industry and occupation
Published Date:Mar 31 2014
Source:Leuk Lymphoma. 55(11):2584-2591.
Acute Myeloid Leukemia
Aged, 80 And Over
Pubmed Central ID:PMC4534715
Funding:1U58DP000807-3/DP/NCCDPHP CDC HHS/United States
CC999999/Intramural CDC HHS/United States
N01-PC-2010-00035/PC/NCI NIH HHS/United States
Description:Acute myeloid leukemia (AML) is the most common type of leukemia found in adults. Identifying jobs that pose a risk for AML may be useful for identifying new risk factors. A matched case-control analysis was conducted using California Cancer Registry data from 1988 to 2007. This study included 8999 cases of AML and 24 822 controls. Industries with a statistically significant increased AML risk were construction (matched odds ratio [mOR] = 1.13); crop production (mOR = 1.41); support activities for agriculture and forestry (mOR = 2.05); and animal slaughtering and processing (mOR = 2.09). Among occupations with a statistically significant increased AML risk were miscellaneous agricultural workers (mOR = 1.76); fishers and related fishing workers (mOR = 2.02); nursing, psychiatric and home health aides (mOR = 1.65); and janitors and building cleaners (mOR = 1.54). Further investigation is needed to confirm study findings and to identify specific exposures responsible for the increased risks.
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