Details:

Alternative Title:
J Occup Environ Hyg
Personal Author:
Fleming, Donald A. ; Woskie, Susan R. ; Jones, James H. ; Silver, Sharon R. ; Luo, Lian ; ... More +
Fleming, Donald A. ; Woskie, Susan R. ; Jones, James H. ; Silver, Sharon R. ; Luo, Lian ; Bertke, Stephen J. Less -
Description:
A retrospective exposure assessment was performed for use in a health outcomes study of a facility manufacturing circuit boards, business machines, and other equipment during the years 1969-2002. A matrix was developed identifying chemical use by department-year based on company-provided information. Use of six chemical agents (fiberglass, lead, methylene chloride, methyl chloroform, perchloroethylene, and trichloroethylene) and six chemical classes (acid-base, aromatic hydrocarbons, chlorinated hydrocarbons, other hydrocarbons, chlorofluorocarbons, and metals), and general (including unspecified) chemicals was identified. The matrix also contained an assignment for each department-year categorizing the potential for use of chemicals as negligible, intermittent/incidental, or routine. These department-based exposure matrix data were combined with work history data to provide duration of potential chemical use for workers. Negligible, intermittent/incidental or routine extent-of-chemical-use categories comprised 42.6%, 39.4%, and 17.9%, respectively, of total person-years of employment. Cumulative exposure scores were also developed, representing a relative measure of the cumulative extent of potential exposure to the six chemical agents, six chemical classes, and general (including unspecified) chemicals. Additionally, the study period was divided into manufacturing eras showing trends in chemical use, and showing that process use of trichloroethylene and methylene chloride ended in the mid-1980s and the mid-1990s, respectively. This approach may be useful in other assessments addressing a variety of chemicals, and with data constraints common to retrospective chemical exposure studies.
Subjects:
[+]
Air Pollutants, Occupational Article Chlorinated Solvents Circuit Board Manufacture Electronics Exposure Matrix Exposure Score Glass Humans Hydrocarbons, Halogenated Inorganic Chemicals Lead Metals Occupational Exposure Occupations Organic Chemicals Perchloroethylene Retrospective Studies Substrate Production Trichloroethylene
Source:
J Occup Environ Hyg. 2014; 11(5):292-305.
Pubmed ID:
24224613
Pubmed Central ID:
PMC4517462
Document Type:
Journal Article
Funding:
DMF9/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:bb8b9f931767963f5a6d7304a8a0309bd0cea824db004cc4067f7acb490fc46e
Download URL:
https://stacks.cdc.gov/view/cdc/32461/cdc_32461_DS1.pdf
File Type:

Supporting Files

• 	NIHMS704286-supplement-Supp_File.docx	docx
  	nihms704286.nxml	txt
  	nihms704286f1.gif	gif
  	nihms704286f1.jpg	jpeg
  	nihms704286f2.gif	gif
  	nihms704286f2.jpg	jpeg

More +