Risk Factors for and Estimated Incidence of Community-associated Clostridium difficile Infection, North Carolina, USA1

Kutty, Preeta K.; Woods, Christopher W.; Sena, Arlene C.; Benoit, Stephen R.; Naggie, Susanna; Frederick, Joyce; Evans, Sharon; Engel, Jeffery; McDonald, L. Clifford

i

Risk Factors for and Estimated Incidence of Community-associated Clostridium difficile Infection, North Carolina, USA1

Supporting Files Public Domain

Feb 2010
By Kutty, Preeta K. ; Woods, Christopher W. ; Sena, Arlene C. ; ...

File Language:

English

Details

Alternative Title:

Emerg Infect Dis
Personal Author:

Kutty, Preeta K. ; Woods, Christopher W. ; Sena, Arlene C. ; Benoit, Stephen R. ; Naggie, Susanna ; Frederick, Joyce ; Evans, Sharon ; Engel, Jeffery ; McDonald, L. Clifford
Description:

We determined estimated incidence of and risk factors for community-associated Clostridium difficile infection (CA-CDI) among patients treated at 6 North Carolina hospitals. CA-CDI case-patients were defined as adults (>18 years of age) with a positive stool test result for C. difficile toxin and no hospitalization within the prior 8 weeks. CA-CDI incidence was 21 and 46 per 100,000 person-years in Veterans Affairs (VA) outpatients and Durham County populations, respectively. VA case-patients were more likely than controls to have received antimicrobial drugs (adjusted odds ratio [aOR] 17.8, 95% confidence interval [CI] 6.6-48] and to have had a recent outpatient visit (aOR 5.1, 95% CI 1.5-17.9). County case-patients were more likely than controls to have received antimicrobial drugs (aOR 9.1, 95% CI 2.9-28.9), to have gastroesophageal reflux disease (aOR 11.2, 95% CI 1.9-64.2), and to have cardiac failure (aOR 3.8, 95% CI 1.1-13.7). Risk factors for CA-CDI overlap with those for healthcare-associated infection.
Subjects:

Adult Aged Aged, 80 And Over Age Distribution Bacterial Proteins Bacterial Toxins Case-Control Studies Clostridium Infections Community-Acquired Infections Dysentery Enterotoxins Feces Female Humans Incidence Male Middle Aged Odds Ratio Prejudice Research Risk Factors Veterans Young Adult
Source:

Emerg Infect Dis. 16(2):198-204.
Document Type:

Journal Article
Place as Subject:

North Carolina
Location:

North America
Volume:

16
Issue:

2
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

urn:sha256:74ce52e5ba1cf854533f7856b5be8f57aa79bd62e9ec9a280639e67d5a0a5f53
Download URL:

https://stacks.cdc.gov/view/cdc/3233/cdc_3233_DS1.pdf
File Type:

[PDF - 189.39 KB ]

File Language:

English

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