Psychosocial Burden and Glycemic Control During the First Six Years of Diabetes: Results from the SEARCH for Diabetes in Youth Study

Details

• Alternative Title:
  J Adolesc Health
• Personal Author:
  Hood, Korey K. ; Beavers, Daniel P. ; Yi-Frazier, Joyce ; Bell, Ronny ; Dabelea, Dana ; Mckeown, Robert E. ; Lawrence, Jean M.
• Corporate Authors:
  SEARCH for Diabetes in Youth Study Group
• Description:
  Purpose
  
  To evaluate the psychosocial burden of adolescents with diabetes, determine the trajectory of psychosocial burden, and examine the interdependent relationships between psychosocial burden and glycemic control across the first six years of diabetes.
  
  Methods
  
  Data from SEARCH for Diabetes in Youth, an observational study of U.S. children diagnosed with diabetes before age 20 years, were collected during study visits conducted at baseline and then 12, 24, and 60 months after baseline. Blood was drawn, clinical and demographic information was collected, and psychosocial burden was evaluated using standardized depression and generic and diabetes-specific health-related quality of life (QOL) surveys.
  
  Results
  
  Among the 1,307 adolescents (mean age 14.1±2.5 years) with baseline data, 1,026 had type 1 diabetes and 281 had type 2 diabetes. For those with a 60-month follow-up visit, A1c values rose 1.5% from baseline (type 1 - 7.7% to 9.3%; type 2 - 7.3% to 8.8%). Adolescents with type 2 diabetes reported more depression and poorer QOL than adolescents with type 1 diabetes. For each diabetes type, there were similar baseline risk factors for higher A1c values; longer diabetes duration, ethnic minority status, and declining diabetes QOL (p<0.05). However, youth with type 2 had higher A1c values with increasing generic QOL, an unexpected finding. Younger adolescents with type 1 diabetes had higher A1c values at study's end.
  
  Conclusions
  
  Significant deterioration in glycemic control marks the first six years of diabetes for adolescents. Psychosocial burden, particularly poor diabetes-specific QOL, is a contributor to suboptimal glycemic outcomes.
  
  
• Keywords:
  Adolescent Blood Glucose Depression Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Female Glycated Hemoglobin Glycemic Control Humans Male Minority Groups Pediatric Diabetes Psychosocial Burden Quality Of Life Type 1 Diabetes Type 2 Diabetes

  More +
• Source:
  J Adolesc Health. 2014; 55(4):498-504
• Pubmed ID:
  24815959
• Pubmed Central ID:
  PMC4497539
• Document Type:
  Journal Article
• Funding:
  P30 DK057516/DK/NIDDK NIH HHSUnited States/ ; M01RR00037/RR/NCRR NIH HHSUnited States/ ; U18 DP002710/DP/NCCDPHP CDC HHSUnited States/ ; M01 RR000069/RR/NCRR NIH HHSUnited States/ ; UL1 TR000154/TR/NCATS NIH HHSUnited States/ ; U18 DP002714/DP/NCCDPHP CDC HHSUnited States/ ; U01 DP000248/DP/NCCDPHP CDC HHSUnited States/ ; M01 RR000037/RR/NCRR NIH HHSUnited States/ ; P30 DK57516/DK/NIDDK NIH HHSUnited States/ ; U18 DP002709/DP/NCCDPHP CDC HHSUnited States/ ; UL1 TR001082/TR/NCATS NIH HHSUnited States/ ; UL1 TR000423/TR/NCATS NIH HHSUnited States/ ; U01 DP000250/DP/NCCDPHP CDC HHSUnited States/ ; HIR 10-001/HX/HSRD VAUnited States/ ; U01 DP000247/DP/NCCDPHP CDC HHSUnited States/ ; U18 DP003256/DP/NCCDPHP CDC HHSUnited States/ ; U01 DP000245/DP/NCCDPHP CDC HHSUnited States/ ; DP-05-069/DP/NCCDPHP CDC HHSUnited States/ ; DP-10-001/DP/NCCDPHP CDC HHSUnited States/ ; U01 DP000244/DP/NCCDPHP CDC HHSUnited States/ ; 1UL1RR026314-01/RR/NCRR NIH HHSUnited States/ ; UL1 RR029882/RR/NCRR NIH HHSUnited States/ ; M01 RR00069/RR/NCRR NIH HHSUnited States/ ; U01 DP000246/DP/NCCDPHP CDC HHSUnited States/ ; U01 DP000254/DP/NCCDPHP CDC HHSUnited States/ ; UL1 RR026314/RR/NCRR NIH HHSUnited States/ ; U18 DP002708/DP/NCCDPHP CDC HHSUnited States/ ; UL1RR029882/RR/NCRR NIH HHSUnited States/
• Volume:
  55
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e3471ce3c1470e9c6f15257d4c91c210201bbfb141ef099e5031e689010885a7
• Download URL:
  https://stacks.cdc.gov/view/cdc/32045/cdc_32045_DS1.pdf
• File Type:
  [PDF - 182.59 KB ]