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Lack of Protection Against Ebola Virus from Chloroquine in Mice and Hamsters
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Jun 2015
Source: Emerg Infect Dis. 21(6):1065-1067. -
Alternative Title:Emerg Infect Dis
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Description:The antimalarial drug chloroquine has been suggested as a treatment for Ebola virus infection. Chloroquine inhibited virus replication in vitro, but only at cytotoxic concentrations. In mouse and hamster models, treatment did not improve survival. Chloroquine is not a promising treatment for Ebola. Efforts should be directed toward other drug classes.
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