Details:

Alternative Title:
Emerg Infect Dis
Publisher's site:
http://dx.doi.org/10.3201/eid2106.150176
Personal Author:
Falzarano, Darryl ; Safronetz, David ; Prescott, Joseph ; Marzi, Andrea ; Feldmann, Friederike ; ... More +
Falzarano, Darryl ; Safronetz, David ; Prescott, Joseph ; Marzi, Andrea ; Feldmann, Friederike ; Feldmann, Heinz Less -
Description:
The antimalarial drug chloroquine has been suggested as a treatment for Ebola virus infection. Chloroquine inhibited virus replication in vitro, but only at cytotoxic concentrations. In mouse and hamster models, treatment did not improve survival. Chloroquine is not a promising treatment for Ebola. Efforts should be directed toward other drug classes.
Subject:
[+]
Animals
Antiviral Agents
Cell Line
Chloroquine
Cricetinae
Disease Models, Animal
Ebolavirus/drug Effects
Hemorrhagic Fever, Ebola
Mice
Viral Load
Virus Replication

Source:
Emerg Infect Dis. 21(6):1065-1067.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:78d42faa9c355ae6a8446ff60e3c85673a78cca9737544d2f12422f2c5d4d0fd
File Type:

Supporting Files

• 	15-0176-F1.gif	gif
  	15-0176-F1.jpg	jpeg
  	15-0176-F2.gif	gif
  	15-0176-F2.jpg	jpeg
  	15-0176.nxml	txt
  	license.txt	txt

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