Exclusion of Progressive Brain Disorders of Childhood for a Cerebral Palsy Monitoring System: A Public Health Perspective

Details

• Alternative Title:
  J Registry Manag
• Personal Author:
  Olney, Richard S. ; Doernberg, Nancy S. ; Yeargin-Allsopp, Marshalyn
• Description:
  Background
  
  Cerebral palsy (CP) is defined by its nonprogressive features. Therefore, a standard definition and list of progressive disorders to exclude would be useful for CP monitoring and epidemiologic studies.
  
  Methods
  
  We reviewed the literature on this topic to 1) develop selection criteria for progressive brain disorders of childhood for public health surveillance purposes, 2) identify categories of disorders likely to include individual conditions that are progressive, and 3) ascertain information about the relative frequency and natural history of candidate disorders.
  
  Results
  
  Based on 19 criteria that we developed, we ascertained a total of 104 progressive brain disorders of childhood, almost all of which were Mendelian disorders.
  
  Discussion
  
  Our list is meant for CP surveillance programs and does not represent a complete catalog of progressive genetic conditions, nor is the list meant to comprehensively characterize disorders that might be mistaken for cerebral palsy. The criteria for progressive disorders that we developed could be applied by public health investigators in the future, as more children with very rare conditions are followed and new candidate disorders are identified.
  
  
• Subjects:
  Brain Diseases Cerebral Palsy Disease Progression Fetal Death Humans Infant Infant Mortality Public Health Surveillance
• Keywords:
  Cerebral Palsy Neurodegenerative Disease Population Surveillance Public Health
• Source:
  J Registry Manag. 41(4):182-189
• Pubmed ID:
  25803631
• Pubmed Central ID:
  PMC4427048
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  41
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:02ab0413d03947b754c62bb1b56a3e94926db37843561bc90d2333e7806f85991b86d22f670b8b2a89dbd80757ceb060ed502303b8df51f11fc7816fb887d6b4
• Download URL:
  https://stacks.cdc.gov/view/cdc/31013/cdc_31013_DS1.pdf
• File Type:
  [PDF - 176.09 KB ]