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Recent US Case of Variant Creutzfeldt-Jakob Disease—Global Implications
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May 2015
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Source: Emerg Infect Dis. 21(5):750-759.
[PDF-2.48 MB]
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Alternative Title:Emerg Infect Dis
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Description:Variant Creutzfeldt-Jakob disease (vCJD) is a rare, fatal prion disease resulting from transmission to humans of the infectious agent of bovine spongiform encephalopathy. We describe the clinical presentation of a recent case of vCJD in the United States and provide an update on diagnostic testing. The location of this patient's exposure is less clear than those in the 3 previously reported US cases, but strong evidence indicates that exposure to contaminated beef occurred outside the United States more than a decade before illness onset. This case exemplifies the persistent risk for vCJD acquired in unsuspected geographic locations and highlights the need for continued global surveillance and awareness to prevent further dissemination of vCJD.
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