Recent US Case of Variant Creutzfeldt-Jakob Disease—Global Implications

Maheshwari, Atul; Fischer, Michael; Gambetti, Pierluigi; Parker, Alicia; Ram, Aarthi; Soto, Claudio; Concha-Marambio, Luis; Cohen, Yvonne; Belay, Ermias D.; Maddox, Ryan A.; Mead, Simon; Goodman, Clay; Kass, Joseph S.; Schonberger, Lawrence B.; Hussein, Haitham M.

doi:10.3201/eid2105.142017

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Recent US Case of Variant Creutzfeldt-Jakob Disease—Global Implications

Published Date:

May 2015

Publisher's site:

http://dx.doi.org/10.3201/eid2105.142017 New Site Icon

Source:

Emerg Infect Dis. 21(5):750-759.

[PDF-2.48 MB]

Details:

Personal Authors:

Maheshwari, Atul ; Fischer, Michael ; Gambetti, Pierluigi ; Parker, Alicia ; Ram, Aarthi ; ... More ▼

Keywords:

[+]

Description:

Variant Creutzfeldt-Jakob disease (vCJD) is a rare, fatal prion disease resulting from transmission to humans of the infectious agent of bovine spongiform encephalopathy. We describe the clinical presentation of a recent case of vCJD in the United States and provide an update on diagnostic testing. The location of this patient's exposure is less clear than those in the 3 previously reported US cases, but strong evidence indicates that exposure to contaminated beef occurred outside the United States more than a decade before illness onset. This case exemplifies the persistent risk for vCJD acquired in unsuspected geographic locations and highlights the need for continued global surveillance and awareness to prevent further dissemination of vCJD.

Document Type:

Journal Article

Collection(s):

CDC Public Access
Emerging Infectious Diseases

Supporting Files:

	14-2017-F1.gif	image/gif
	14-2017-F1.jpg	image/jpeg
	14-2017-F2.gif	image/gif
	14-2017-F2.jpg	image/jpeg
	14-2017-F3.gif	image/gif
	14-2017-F3.jpg	image/jpeg
	14-2017-F4.gif	image/gif
	14-2017-F4.jpg	image/jpeg

No Related Documents.

You May Also Like:

A case cluster of variant Creutzfeldt-Jakob disease linked to the Kingdom of Saudi Arabia

Personal Author:

Coulthart, Michael B.; Geschwind, Michael D.; Qureshi, Shireen; Phielipp, Nicolas; Demarsh, Alex; Abrams, Joseph Y.; Belay, Ermias; Gambetti, Pierluigi; Jansen, Gerard H.; Lang, Anthony E.; Schonberger, Lawrence B.;

Published:

Oct 2016

Source:

Brain. 139(Pt 10):2609-2616.

Description:

As of mid-2016, 231 cases of variant Creutzfeldt-Jakob disease-the human form of a prion disease of cattle, bovine spongiform encephalopathy-have been reported from 12 countries. With few exceptions, the affected individuals had histories of extended...

File Type:

[PDF - 511.43 KB]
On the Question of Sporadic or Atypical Bovine Spongiform Encephalopathy and Creutzfeldt-Jakob Disease

Personal Author:

Brown, Paul; McShane, Lisa M.; Zanusso, Gianluigi; Detwiler, Linda;

Published:

Dec 2006

Source:

Emerg Infect Dis. 12(12):1816-1821.

Description:

Strategies to investigate the possible existence of sporadic bovine spongiform encephalopathy (BSE) require systematic testing programs to identify cases in countries considered to have little or no risk of orally acquired disease or to detect a stab...

File Type:

[PDF - 176.84 KB]
Bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease: background, evolution, and current concerns.

Personal Author:

Brown, P.; Will, R. G.; Bradley, R.; Asher, D. M.; Detwiler, L.;

Published:

2001 Jan-Feb

Source:

Emerg Infect Dis. 7(1):6-16.

Description:

The epidemic of bovine spongiform encephalopathy (BSE) in the United Kingdom, which began in 1986 and has affected nearly 200,000 cattle, is waning to a conclusion, but leaves in its wake an outbreak of human Creutzfeldt-Jakob disease, most probably ...

File Type:

[PDF - 129.36 KB]
Emerging infectious diseases--United Kingdom.

Personal Author:

Walford, D.; Noah, N.;

Published:

1999 Mar-Apr

Source:

Emerg Infect Dis. 5(2):189-194.

File Type:

[PDF - 173.36 KB]
Sporadic Creutzfeldt-Jakob Disease in 2 Plasma Product Recipients, United Kingdom

Personal Author:

Urwin, Patrick; Thanigaikumar, Kumar; Ironside, James W.; Molesworth, Anna; Knight, Richard S.; Hewitt, Patricia E.; Llewelyn, Charlotte; Mackenzie, Jan; Will, Robert G.;

Published:

Jun 2017

Source:

Emerg Infect Dis. 23(6):893-897.

Description:

Sporadic Creutzfeldt-Jakob disease (sCJD) has not been previously reported in patients with clotting disorders treated with fractionated plasma products. We report 2 cases of sCJD identified in the United Kingdom in patients with a history of extende...

File Type:

[PDF - 1.27 MB]