Comparative Sequence Analyses of La Crosse Virus Strain Isolated from Patient with Fatal Encephalitis, Tennessee, USA

Lambert, Amy J.; Fryxell, Rebecca Trout; Freyman, Kimberly; Ulloa, Armando; Velez, Jason O.; Paulsen, Dave; Lanciotti, Robert S.; Moncayo, Abelardo

doi:10.3201/eid2105.141992

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Comparative Sequence Analyses of La Crosse Virus Strain Isolated from Patient with Fatal Encephalitis, Tennessee, USA

May 2015
By Lambert, Amy J. ; Fryxell, Rebecca Trout ; Freyman, Kimberly ; ...
http://dx.doi.org/10.3201/eid2105.141992
Source: Emerg Infect Dis. 21(5):833-836.

[PDF-694.76 KB]

English

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Details:

Alternative Title:

Emerg Infect Dis
Personal Author:

Lambert, Amy J. ; Fryxell, Rebecca Trout ; Freyman, Kimberly ; Ulloa, Armando ; Velez, Jason O. ; ... More +

Lambert, Amy J. ; Fryxell, Rebecca Trout ; Freyman, Kimberly ; Ulloa, Armando ; Velez, Jason O. ; Paulsen, Dave ; Lanciotti, Robert S. ; Moncayo, Abelardo Less -
Description:

We characterized a La Crosse virus (LACV) isolate from the brain of a child who died of encephalitis-associated complications in eastern Tennessee, USA, during summer 2012. We compared the isolate with LACV sequences from mosquitoes collected near the child's home just after his postmortem diagnosis. In addition, we conducted phylogenetic analyses of these and other sequences derived from LACV strains representing varied temporal, geographic, and ecologic origins. Consistent with historical findings, results of these analyses indicate that a limited range of LACV lineage I genotypes is associated with severe clinical outcomes.
Subjects:

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Animals Child Encephalitis, California Fatal Outcome Genome, Viral Humans La Crosse Virus Male Phylogeny Research Rna, Viral Serotyping
Source:

Emerg Infect Dis. 21(5):833-836.
Document Type:

Journal Article
Place as Subject:

Tennessee
Collection(s):

Emerging Infectious Diseases
Main Document Checksum:

[+]

urn:sha256:4aeab15b29a5dc5e256c69965a62456210626e233fd378401a5e7d5f73108afa
Download URL:

https://stacks.cdc.gov/view/cdc/30919/cdc_30919_DS1.pdf
File Type:

	14-1992-F.gif	gif
	14-1992-F.jpg	jpeg
	14-1992.nxml	txt
	license.txt	txt

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