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Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant
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  1. Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Isolated from Poultry, Vietnam, 2009–2011
    Personal Author:
    Nguyen, Ha T.; Nguyen, Tung; Mishin, Vasiliy P.; Sleeman, Katrina; Balish, Amanda; Jones, Joyce; Creanga, Adrian; Marjuki, Henju; Uyeki, Timothy M.; Nguyen, Dang H.; Nguyen, Diep T.; Do, Hoa T.; Klimov, Alexander I.; Davis, Charles T.; Gubareva, Larisa V.;
    Published:
    Dec 2013
    Source:
    Emerg Infect Dis. 19(12):1963-1971.
    Description:
    We assessed drug susceptibilities of 125 avian influenza A(H5N1) viruses isolated from poultry in Vietnam during 2009-2011. Of 25 clade 1.1 viruses, all possessed a marker of resistance to M2 blockers amantadine and rimantadine; 24 were inhibited by ...
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  2. Microevolution of Highly Pathogenic Avian Influenza A(H5N1) Viruses Isolated from Humans, Egypt, 2007–2011
    Personal Author:
    Younan, Mary; Poh, Mee Kian; Elassal, Emad; Davis, Todd; Rivailler, Pierre; Balish, Amanda L.; Simpson, Natosha; Jones, Joyce; Deyde, Varough; Loughlin, Rosette; Perry, Ije; Gubareva, Larisa; ElBadry, Maha A.; Truelove, Shaun; Gaynor, Anne M.; Mohareb, Emad; Amin, Magdy; Cornelius, Claire; Pimentel, Guillermo; Earhart, Kenneth; Naguib, Amel; Abdelghani, Ahmed S.; Refaey, Samir; Klimov, Alexander I.; Donis, Ruben O.; Kandeel, Amr;
    Published:
    Jan 2013
    Source:
    Emerg Infect Dis. 19(1):43-50.
    Description:
    We analyzed highly pathogenic avian influenza A(H5N1) viruses isolated from humans infected in Egypt during 2007-2011. All analyzed viruses evolved from the lineage of subtype H5N1 viruses introduced into Egypt in 2006; we found minimal evidence of r...
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  3. Demographic and Clinical Predictors of Mortality from Highly Pathogenic Avian Influenza A (H5N1) Virus Infection: CART Analysis of International Cases
    Personal Author:
    Patel, Rita B.; Mathur, Maya B.; Gould, Michael; Uyeki, Timothy M.; Bhattacharya, Jay; Xiao, Yang; Khazeni, Nayer;
    Published:
    Mar 25 2014
    Source:
    PLoS One. 2014; 9(3).
    Description:
    Background : Human infections with highly pathogenic avian influenza (HPAI) A (H5N1) viruses have occurred in 15 countries, with high mortality to date. Determining risk factors for morbidity and mortality from HPAI H5N1 can inform preventive and the...
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  4. Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China
    Personal Author:
    Gu, Min; Zhao, Guo; Zhao, Kunkun; Zhong, Lei; Huang, Junqing; Wan, Hongquan; Wang, Xiaoquan; Liu, Wenbo; Liu, Huimou; Peng, Daxin; Liu, Xiufan;
    Published:
    Dec 2013
    Source:
    Emerg Infect Dis. 19(12):2021-2024.
    Description:
    We characterized 7 highly pathogenic avian influenza A(H5N1) viruses isolated from poultry in China during 2009-2012 and found that they belong to clade 2.3.4 but do not fit within the 3 defined subclades. Antigenic drift in subtype H5N1 variants may...
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  5. Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)
    Personal Author:
    Lierz, Michael; Hafez, Hafez M.; Klopfleisch, Robert; Lüschow, Dörte; Prusas, Christine; Teifke, Jens P.; Rudolf, Miriam; Grund, Christian; Kalthoff, Donata; Mettenleiter, Thomas; Beer, Martin; Harder, Timm;
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    Nov 2007
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    Emerg Infect Dis. 13(11):1667-1674.
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    Because fatal infections with highly pathogenic avian influenza A (HPAI) virus subtype H5N1 have been reported in birds of prey, we sought to determine detailed information about the birds' susceptibility and protection after vaccination. Ten falcons...
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