Surveillance for Unexplained Deaths and Critical Illnesses

Hajjeh, Rana A.; Relman, David; Cieslak, Paul R.; Sofair, Andre N.; Passaro, Douglas; Flood, Jennifer; Johnson, James; Hacker, Jill K.; Shieh, Wun-Ju; Hendry, R. Michael; Nikkari, Simo; Ladd-Wilson, Stephen; Hadler, James; Rainbow, Jean; Tappero, Jordan W.; Woods, Christopher W.; Conn, Laura; Reagan, Sarah; Zaki, Sherif; Perkins, Bradley A.

doi:10.3201/eid0802.010165

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Surveillance for Unexplained Deaths and Critical Illnesses

Published Date:

Feb 2002

Publisher's site:

http://dx.doi.org/10.3201/eid0802.010165 New Site Icon

Source:

Emerg Infect Dis. 8(2):145-153.

[PDF-189.07 KB]

Details:

Personal Authors:

Hajjeh, Rana A. ; Relman, David ; Cieslak, Paul R. ; Sofair, Andre N. ; Passaro, Douglas ; ... More ▼

Corporate Authors:

for the Unexplained Deaths . Critical Illness Working Group .

Keywords:

[+]

Description:

Population-based surveillance for unexplained death and critical illness possibly due to infectious causes (UNEX) was conducted in four U.S. Emerging Infections Program sites (population 7.7 million) from May 1, 1995, to December 31, 1998, to define the incidence, epidemiologic features, and etiology of this syndrome. A case was defined as death or critical illness in a hospitalized, previously healthy person, 1 to 49 years of age, with infection hallmarks but no cause identified after routine testing. A total of 137 cases were identified (incidence rate 0.5 per 100,000 per year). Patients' median age was 20 years, 72 (53%) were female, 112 (82%) were white, and 41 (30%) died. The most common clinical presentations were neurologic (29%), respiratory (27%), and cardiac (21%). Infectious causes were identified for 34 cases (28% of the 122 cases with clinical specimens); 23 (68%) were diagnosed by reference serologic tests, and 11 (32%) by polymerase chain reaction-based methods. The UNEX network model would improve U.S. diagnostic capacities and preparedness for emerging infections.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases
CDC Public Access

Main Document Checksum:

[+]

Supporting Files:

	license.txt	text/plain
	01-0165-F1.gif	image/gif
	01-0165-F1.jpg	image/jpeg
	01-0165-F2.gif	image/gif
	01-0165-F2.jpg	image/jpeg
	01-0165_app-s1.pdf	application/pdf
	01-0165_app-s2.pdf	application/pdf
	01-0165_app-s3.pdf	application/pdf
	01-0165_FinalR.nxml	text/plain

No Related Documents.

You May Also Like:

CDC Grand Rounds: Discovering New Diseases via Enhanced Partnership Between Public Health and Pathology Experts

Personal Author:

Zaki, Sherif; Blau, Dianna M.; Hughes, James M.; Nolte, Kurt B.; Lynfield, Ruth; Carr, Wendy; Popovic, Tanja;

Published:

Feb 14 2014

Source:

MMWR Morb Mortal Wkly Rep. 2014; 63(6):121-126.

Description:

Despite advances in public health, medicine, and technology, infectious diseases remain a major source of illness and death worldwide. In the United States alone, unexplained deaths resulting from infectious disease agents have an estimated annual in...

File Type:

[PDF - 340.86 KB]
Unexplained Deaths and Critical Illnesses of Suspected Infectious Cause, Taiwan, 2000–2005

Personal Author:

Wang, Tsung-Hsi; Wei, Kuo-Chen; Jiang, Donald Dah-Shyong; Chiu, Chan-Hsian; Chang, Shan-Chwen; Wang, Jung-Der;

Published:

Oct 2008

Source:

Emerg Infect Dis. 14(10):1653-1655

Description:

We report 5 years' surveillance data from the Taiwan Centers for Disease Control on unexplained deaths and critical illnesses suspected of being caused by infection. A total of 130 cases were reported; the incidence rate was 0.12 per 100,000 person-y...

File Type:

[PDF - 92.66 KB]
Disease Surveillance and the Academic, Clinical, and Public Health Communities

Personal Author:

Pinner, Robert W.; Rebmann, Catherine A.; Schuchat, Anne; Hughes, James M.;

Published:

Jul 2003

Source:

Emerg Infect Dis. 9(7):781-787.

Description:

The Emerging Infections Programs (EIPs), a population-based network involving 10 state health departments and the Centers for Disease Control and Prevention, complement and support local, regional, and national surveillance and research efforts. EIPs...

File Type:

[PDF - 285.46 KB]
Pandemic (H1N1) 2009–associated Deaths Detected by Unexplained Death and Medical Examiner Surveillance

Personal Author:

Lees, Christine H.; Avery, Catherine; Asherin, Ryan; Rainbow, Jean; Danila, Richard; Smelser, Chad; Schmitz, Ann; Ladd-Wilson, Stephen; Nolte, Kurt B.; Nagle, Kayla; Lynfield, Ruth;

Published:

Aug 2011

Source:

Emerg Infect Dis. 17(8):1479-1483.

Description:

During the pandemic (H1N1) 2009 outbreak, Minnesota, New Mexico, and Oregon used several surveillance methods to detect associated deaths. Surveillance using unexplained death and medical examiner data allowed for detection of 34 (18%) pandemic (H1N1...

File Type:

[PDF - 251.74 KB]
MMWR. Morbidity and mortality weekly report, Vol. 63, no. 6, February 14, 2014

Corporate Author:

Centers for Disease Control and Prevention (U.S.)

Published:

February 14, 2014

Series:

MMWR. Morbidity and mortality weekly report ; v. 63, no. 6

Description:

CDC Grand Rounds: Discovering New Diseases via Enhanced Partnership Between Public Health and Pathology Experts -- Progress of Health Plans Toward Meeting the Target for High Blood Pressure Control — United States, 2010–2012 -- Notes from the Fie...

File Type:

[PDF - 603.65 KB]