An Outbreak of Rift Valley Fever in Northeastern Kenya, 1997-98

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Woods, Christopher W. ; Karpati, Adam M. ; Grein, Thomas ; McCarthy, Noel ; Gaturuku, Peter ; Muchiri, Eric ; Dunster, Lee ; Henderson, Alden ; Khan, Ali S. ; Swanepoel, Robert ; Bonmarin, Isabelle ; Martin, Louise ; Mann, Philip ; Smoak, Bonnie L. ; Ryan, Michael ; Ksiazek, Thomas G. ; Arthur, Ray R. ; Ndikuyeze, Andre ; Agata, Naphtali N. ; Peters, Clarence J
• Corporate Authors:
  World Health Organization Hemorrhagic Fever Task Force
• Description:
  In December 1997, 170 hemorrhagic fever-associated deaths were reported in Garissa District, Kenya. Laboratory testing identified evidence of acute Rift Valley fever virus (RVFV). Of the 171 persons enrolled in a cross-sectional study, 31(18%) were anti-RVFV immunoglobulin (Ig) M positive. An age-adjusted IgM antibody prevalence of 14% was estimated for the district. We estimate approximately 27,500 infections occurred in Garissa District, making this the largest recorded outbreak of RVFV in East Africa. In multivariable analysis, contact with sheep body fluids and sheltering livestock in one s home were significantly associated with infection. Direct contact with animals, particularly contact with sheep body fluids, was the most important modifiable risk factor for RVFV infection. Public education during epizootics may reduce human illness and deaths associated with future outbreaks.
• Subjects:
  Adolescent Adult Age Distribution Antibodies, Viral Child Cross-Sectional Studies Disease Outbreaks Enzyme-Linked Immunosorbent Assay Female Humans Immunoglobulin M Male Middle Aged Orthobunyavirus Population Surveillance Research Rift Valley Fever Risk Factors Time Factors

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• Source:
  Emerg Infect Dis. 8(2):138-144.
• Document Type:
  Journal Article
• Place as Subject:
  Kenya
• Location:
  Africa
• Volume:
  8
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:aee01b6f46e336999d6b7cf889f9be2ebb1563baf24c145807550675bcc7d3bd
• Download URL:
  https://stacks.cdc.gov/view/cdc/3066/cdc_3066_DS1.pdf
• File Type:
  [PDF - 106.61 KB ]